Strain Summary[not specified]-Msh2^tm2.1Rak Tg(Vil1-cre)997Gum

Strain Name	[not specified]-Msh2^tm2.1Rak Tg(Vil1-cre)997Gum
Strain Type(s)	targeted mutation (conditional) • transgenic
Strain Synonym(s)	Msh2^LoxP/LoxP • Villin-Cre Msh2^LoxP/LoxP • Villin-Cre Msh2^-/- • [not specified]-Msh2^tm2.1Rak Tg(Vil-cre)997Gum
Description	Homozygous Msh2 mutant, transgenic mice on an unspecified background with possible contributions from "129/Sv", C57BL/6J, and/or SJL.
Strain Genetics	List all models in MMHCdb carrying the Tg(Vil1-cre)997Gum allele Tg(Vil1-cre)997Gum
	List all models in MMHCdb carrying the Msh2^tm2.1Rak allele Msh2^tm2.1Rak / Msh2^tm2.1Rak

Models
18 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Intestine - Large Intestine - Colon adenocarcinoma	Intestine - Large Intestine - Colon	BEZ235 (NVP-BEZ235-AN)				observed	References: Kucherlapati MH, PLoS One 2013;8(7):e68817
Intestine - Large Intestine - Colon adenocarcinoma - intramucosal	Intestine - Large Intestine - Colon	BEZ235 (NVP-BEZ235-AN)				0	References: Kucherlapati MH, PLoS One 2013;8(7):e68817
Intestine - Large Intestine - Colon adenoma	Intestine - Large Intestine - Colon	BEZ235 (NVP-BEZ235-AN)				observed	References: Kucherlapati MH, PLoS One 2013;8(7):e68817
Intestine - Large Intestine - Colon adenoma	Intestine - Large Intestine - Colon					100	References: Kucherlapati MH, PLoS One 2013;8(7):e68817
Intestine - Small Intestine adenocarcinoma	Intestine - Small Intestine					observed - high	References: Kucherlapati MH, PLoS One 2013;8(7):e68817
Intestine - Small Intestine adenocarcinoma	Intestine - Small Intestine	BEZ235 (NVP-BEZ235-AN)				observed	References: Kucherlapati MH, PLoS One 2013;8(7):e68817
Intestine - Small Intestine adenocarcinoma	Intestine - Small Intestine	AZD6244 (ARRY-142886) ⋅ BEZ235 (NVP-BEZ235-AN)				observed	References: Kucherlapati MH, PLoS One 2013;8(7):e68817
Intestine - Small Intestine adenocarcinoma - intramucosal	Intestine - Small Intestine					observed	References: Kucherlapati MH, PLoS One 2013;8(7):e68817
Intestine - Small Intestine adenocarcinoma - intramucosal	Intestine - Small Intestine	BEZ235 (NVP-BEZ235-AN)				0	References: Kucherlapati MH, PLoS One 2013;8(7):e68817
Intestine - Small Intestine adenocarcinoma - intramucosal	Intestine - Small Intestine	AZD6244 (ARRY-142886) ⋅ BEZ235 (NVP-BEZ235-AN)				0	References: Kucherlapati MH, PLoS One 2013;8(7):e68817
Intestine - Small Intestine adenoma	Intestine - Small Intestine					observed	References: Kucherlapati MH, PLoS One 2013;8(7):e68817
Intestine - Small Intestine adenoma	Intestine - Small Intestine	BEZ235 (NVP-BEZ235-AN)				observed	References: Kucherlapati MH, PLoS One 2013;8(7):e68817
Intestine - Small Intestine adenoma	Intestine - Small Intestine	AZD6244 (ARRY-142886) ⋅ BEZ235 (NVP-BEZ235-AN)				observed	References: Kucherlapati MH, PLoS One 2013;8(7):e68817
Intestine - Small Intestine tumor	Intestine - Small Intestine					100	References: Kucherlapati MH, PLoS One 2013;8(7):e68817
Intestine adenoma	Intestine					100	References: Kucherlapati MH, PLoS One 2013;8(7):e68817
Intestine tumor	Intestine					100	References: Kucherlapati MH, PLoS One 2013;8(7):e68817
Intestine tumor	Intestine	BEZ235 (NVP-BEZ235-AN)				100	References: Kucherlapati MH, PLoS One 2013;8(7):e68817
Intestine tumor	Intestine	AZD6244 (ARRY-142886) ⋅ BEZ235 (NVP-BEZ235-AN)				100	References: Kucherlapati MH, PLoS One 2013;8(7):e68817