Strain Summary[not specified]-Krastm4Tyj/+ Tg(KRT14-cre/PGR)1Der
Strain Name |
[not specified]-Krastm4Tyj/+ Tg(KRT14-cre/PGR)1Der |
Strain Type(s) |
targeted mutation (conditional) • transgenic |
Strain Synonym(s) |
K14.CrePR1/LSLK-rasG12D • K14Cre-Ras |
Description |
Heterozygous Krastm4Tyj mice containing the Tg(KRT14-cre/PGR)1Der transgene on an unspecified background containing possible contributions from 129S4/SvJae, ICR, and/or FVB. |
Strain Genetics |
Tg(KRT14-cre/PGR)1Der |
| Krastm4Tyj / Kras+ |
| Frequency | ||||||||
|---|---|---|---|---|---|---|---|---|
| Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
| Mouth - Oral mucosa lesion | Mouth - Oral mucosa | RU-486 |
observed |
References: Caulin C, Cancer Res 2004 Aug 1;64(15):5054-8 |
||||
| Oral cavity hyperplasia | Oral cavity | RU-486 |
100 |
References: Caulin C, Cancer Res 2004 Aug 1;64(15):5054-8 |
||||
| Oral cavity hyperplasia | Oral cavity |
observed |
References: Caulin C, Cancer Res 2004 Aug 1;64(15):5054-8 |
|||||
| Oral cavity tumor | Oral cavity | RU-486 |
100 |
References: Caulin C, Cancer Res 2004 Aug 1;64(15):5054-8 |
||||
| Tongue lesion | Tongue | RU-486 |
observed |
References: Caulin C, Cancer Res 2004 Aug 1;64(15):5054-8 |
||||