Strain Summary[not specified]-Kras^tm4Tyj/+ Tg(KRT5-cre/PGR)1Der

Strain Name	[not specified]-Kras^tm4Tyj/+ Tg(KRT5-cre/PGR)1Der
Strain Type(s)	targeted mutation (conditional) • transgenic
Strain Synonym(s)	K5.CrePR1/LSL-K-rasG12D* • K5Cre*-Ras
Description	Heterozygous Kras^tm4Tyj mice containing the Tg(KRT5-cre/PGR)1Der transgene on an unspecified background containing possible contributions from 129S4/SvJae, ICR, and/or FVB.
Strain Genetics	List all models in MMHCdb carrying the Kras^tm4Tyj allele Kras^tm4Tyj / Kras⁺
	List all models in MMHCdb carrying the Tg(KRT5-cre/PGR)1Der allele Tg(KRT5-cre/PGR)1Der

Models
9 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Mouth - Oral mucosa papilloma - exophytic	Mouth - Oral mucosa	RU-486				observed	References: Caulin C, Cancer Res 2004 Aug 1;64(15):5054-8
Mouth - Palate papilloma - exophytic	Mouth - Palate	RU-486				observed	References: Caulin C, Cancer Res 2004 Aug 1;64(15):5054-8
Oral cavity hyperplasia	Oral cavity	RU-486				observed	References: Caulin C, Cancer Res 2004 Aug 1;64(15):5054-8
Oral cavity hyperplasia	Oral cavity					0	References: Caulin C, Cancer Res 2004 Aug 1;64(15):5054-8
Oral cavity papilloma - exophytic	Oral cavity	RU-486				observed	References: Caulin C, Cancer Res 2004 Aug 1;64(15):5054-8
Oral cavity squamous cell papilloma	Oral cavity	RU-486				observed	References: Caulin C, Cancer Res 2004 Aug 1;64(15):5054-8
Oral cavity tumor	Oral cavity	RU-486				100	References: Caulin C, Cancer Res 2004 Aug 1;64(15):5054-8
Oral cavity tumor	Oral cavity					0	References: Caulin C, Cancer Res 2004 Aug 1;64(15):5054-8
Tongue papilloma - exophytic	Tongue	RU-486				observed	References: Caulin C, Cancer Res 2004 Aug 1;64(15):5054-8

Models