Strain SummaryC57BL/6-ApcMin/+ Lyz2tm1(cre)Ifo Trp53tm1Brn

Strain Name

C57BL/6-ApcMin/+ Lyz2tm1(cre)Ifo Trp53tm1Brn

Strain Type(s)

chemically induced mutation  •  targeted mutation (conditional)  •  targeted mutation (knock-in)

Strain Synonym(s)

ApcMin/+; LysM-p53Flox/Flox

Description

Homozygous Trp53tm1Brn, heterozygous ApcMin, Lyz2tm1(cre)Ifo mice on a C57BL/6 genetic background with possible contribution from C57BL/6J and/or 129P2/OlaHsd.

Strain Genetics

ApcMin / Apc+
Lyz2tm1(cre)Ifo / Lyz2+
Trp53tm1Brn / Trp53tm1Brn

Models

3 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Intestine - Small Intestine adenoma Intestine - Small Intestine

observed

References: He XY, Cell Rep 2015 Nov 3;13(5):888-97

Intestine - Small Intestine polyp Intestine - Small Intestine

observed

References: He XY, Cell Rep 2015 Nov 3;13(5):888-97

Intestine - Small Intestine tumor Intestine - Small Intestine

observed

References: He XY, Cell Rep 2015 Nov 3;13(5):888-97