Strain SummaryC57BL/6-ApcMin/+ Lyz2tm1(cre)Ifo Trp53tm1Brn/+
Strain Name |
C57BL/6-ApcMin/+ Lyz2tm1(cre)Ifo Trp53tm1Brn/+ |
Strain Type(s) |
chemically induced mutation • targeted mutation (conditional) • targeted mutation (knock-in) |
Strain Synonym(s) |
ApcMin/+; LysM-p53Flox/+ |
Description |
Heterozygous Trp53tm1Brn, ApcMin, Lyz2tm1(cre)Ifo mice on a C57BL/6 genetic background with possible contribution from C57BL/6J and/or 129P2/OlaHsd. |
Strain Genetics |
ApcMin / Apc+ |
Lyz2tm1(cre)Ifo / Lyz2+ | |
Trp53tm1Brn / Trp53+ |
Frequency | ||||||||
---|---|---|---|---|---|---|---|---|
Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Intestine - Small Intestine - Distal adenoma | Intestine - Small Intestine - Distal |
observed |
References: He XY, Cell Rep 2015 Nov 3;13(5):888-97 |
|||||
Intestine - Small Intestine - Distal polyp | Intestine - Small Intestine - Distal |
observed |
References: He XY, Cell Rep 2015 Nov 3;13(5):888-97 |
|||||
Intestine - Small Intestine - Proximal adenoma | Intestine - Small Intestine - Proximal |
observed |
References: He XY, Cell Rep 2015 Nov 3;13(5):888-97 |
|||||
Intestine - Small Intestine - Proximal polyp | Intestine - Small Intestine - Proximal |
observed |
References: He XY, Cell Rep 2015 Nov 3;13(5):888-97 |
|||||
Intestine - Small Intestine adenoma | Intestine - Small Intestine |
observed |
References: He XY, Cell Rep 2015 Nov 3;13(5):888-97 |
|||||
Intestine - Small Intestine polyp | Intestine - Small Intestine |
observed |
References: He XY, Cell Rep 2015 Nov 3;13(5):888-97 |
|||||
Intestine adenoma | Intestine |
observed |
References: He XY, Cell Rep 2015 Nov 3;13(5):888-97 |
|||||
Intestine adenoma - microadenoma | Intestine |
observed - 100 |
References: He XY, Cell Rep 2015 Nov 3;13(5):888-97 |
|||||
Intestine tumor | Intestine |
observed |
References: He XY, Cell Rep 2015 Nov 3;13(5):888-97 |