Strain SummaryC57BL/6-ApcMin/+ Lyz2tm1(cre)Ifo/+ Mdm2tm2.1Glo/+ Mdm4tm1Glo/+

Strain Name

C57BL/6-ApcMin/+ Lyz2tm1(cre)Ifo/+ Mdm2tm2.1Glo/+ Mdm4tm1Glo/+

Strain Type(s)

chemically induced mutation  •  targeted mutation (conditional)  •  targeted mutation (knock-in)  •  targeted mutation (knockout)

Strain Synonym(s)

ApcMin/+; LysM-MM

Description

Heterozygous ApcMin, Lyz2tm1(cre)Ifo, Mdm2tm2.1Glo, Mdm4tm1Glo mice on a C57BL/6 genetic background with possible contribution from C57BL/6J, 129P2OlaHsd, and/or 129S7/SvEvBrd.

Strain Genetics

ApcMin / Apc+
Lyz2tm1(cre)Ifo / Lyz2+
Mdm4tm1Glo / Mdm4+
Mdm2tm2.1Glo / Mdm2+

Models

11 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Intestine - Large Intestine - Colon - Distal tumor Intestine - Large Intestine - Colon - Distal dextran sulfate sodium (DSS)

observed

References: He XY, Cell Rep 2015 Nov 3;13(5):888-97

Intestine - Large Intestine - Colon adenocarcinoma Intestine - Large Intestine - Colon dextran sulfate sodium (DSS)

observed

References: He XY, Cell Rep 2015 Nov 3;13(5):888-97

Intestine - Large Intestine - Colon polyp Intestine - Large Intestine - Colon

observed

References: He XY, Cell Rep 2015 Nov 3;13(5):888-97

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon dextran sulfate sodium (DSS)

observed

References: He XY, Cell Rep 2015 Nov 3;13(5):888-97

Intestine - Large Intestine adenocarcinoma Intestine - Large Intestine dextran sulfate sodium (DSS)

0

References: He XY, Cell Rep 2015 Nov 3;13(5):888-97

Intestine - Large Intestine tumor Intestine - Large Intestine dextran sulfate sodium (DSS)

observed

References: He XY, Cell Rep 2015 Nov 3;13(5):888-97

Intestine - Small Intestine polyp Intestine - Small Intestine

observed

References: He XY, Cell Rep 2015 Nov 3;13(5):888-97

Intestine adenoma Intestine

observed

References: He XY, Cell Rep 2015 Nov 3;13(5):888-97

Intestine adenoma - microadenoma Intestine

observed

References: He XY, Cell Rep 2015 Nov 3;13(5):888-97

Intestine polyp Intestine

observed

References: He XY, Cell Rep 2015 Nov 3;13(5):888-97

Intestine tumor Intestine

observed

References: He XY, Cell Rep 2015 Nov 3;13(5):888-97