Strain SummaryC57BL/6-ApcMin/+ Lyz2tm1(cre)Ifo/+ Mdm2tm2.1Glo/+ Mdm4tm1Glo/+
Strain Name |
C57BL/6-ApcMin/+ Lyz2tm1(cre)Ifo/+ Mdm2tm2.1Glo/+ Mdm4tm1Glo/+ |
Strain Type(s) |
chemically induced mutation • targeted mutation (conditional) • targeted mutation (knock-in) • targeted mutation (knockout) |
Strain Synonym(s) |
ApcMin/+; LysM-MM |
Description |
Heterozygous ApcMin, Lyz2tm1(cre)Ifo, Mdm2tm2.1Glo, Mdm4tm1Glo mice on a C57BL/6 genetic background with possible contribution from C57BL/6J, 129P2OlaHsd, and/or 129S7/SvEvBrd. |
Strain Genetics |
ApcMin / Apc+ |
Lyz2tm1(cre)Ifo / Lyz2+ | |
Mdm4tm1Glo / Mdm4+ | |
Mdm2tm2.1Glo / Mdm2+ |
Frequency | ||||||||
---|---|---|---|---|---|---|---|---|
Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Intestine - Large Intestine - Colon - Distal tumor | Intestine - Large Intestine - Colon - Distal | dextran sulfate sodium (DSS) |
observed |
References: He XY, Cell Rep 2015 Nov 3;13(5):888-97 |
||||
Intestine - Large Intestine - Colon adenocarcinoma | Intestine - Large Intestine - Colon | dextran sulfate sodium (DSS) |
observed |
References: He XY, Cell Rep 2015 Nov 3;13(5):888-97 |
||||
Intestine - Large Intestine - Colon polyp | Intestine - Large Intestine - Colon |
observed |
References: He XY, Cell Rep 2015 Nov 3;13(5):888-97 |
|||||
Intestine - Large Intestine - Colon tumor | Intestine - Large Intestine - Colon | dextran sulfate sodium (DSS) |
observed |
References: He XY, Cell Rep 2015 Nov 3;13(5):888-97 |
||||
Intestine - Large Intestine adenocarcinoma | Intestine - Large Intestine | dextran sulfate sodium (DSS) |
0 |
References: He XY, Cell Rep 2015 Nov 3;13(5):888-97 |
||||
Intestine - Large Intestine tumor | Intestine - Large Intestine | dextran sulfate sodium (DSS) |
observed |
References: He XY, Cell Rep 2015 Nov 3;13(5):888-97 |
||||
Intestine - Small Intestine polyp | Intestine - Small Intestine |
observed |
References: He XY, Cell Rep 2015 Nov 3;13(5):888-97 |
|||||
Intestine adenoma | Intestine |
observed |
References: He XY, Cell Rep 2015 Nov 3;13(5):888-97 |
|||||
Intestine adenoma - microadenoma | Intestine |
observed |
References: He XY, Cell Rep 2015 Nov 3;13(5):888-97 |
|||||
Intestine polyp | Intestine |
observed |
References: He XY, Cell Rep 2015 Nov 3;13(5):888-97 |
|||||
Intestine tumor | Intestine |
observed |
References: He XY, Cell Rep 2015 Nov 3;13(5):888-97 |