Strain SummaryC57BL/6-ApcMin/+ Lyz2tm1(cre)Ifo/+ Gt(ROSA)26Sortm1Sor Mdm2tm2.1Glo/+ Mdm4tm1Glo/+

Strain Name

C57BL/6-ApcMin/+ Lyz2tm1(cre)Ifo/+ Gt(ROSA)26Sortm1Sor Mdm2tm2.1Glo/+ Mdm4tm1Glo/+

Strain Type(s)

chemically induced mutation  •  targeted mutation (conditional)  •  targeted mutation (knock-in)  •  targeted mutation (knockout)  •  transgenic

Strain Synonym(s)

ApcMin/+; Rosa26; LysM-MM

Description

Compound mutant mice on a C57BL/6 genetic background with possible contribution from C57BL/6J, 129P2OlaHsd, and/or 129S7/SvEvBrd.

Strain Genetics

ApcMin / Apc+
Lyz2tm1(cre)Ifo / Lyz2+
Gt(ROSA)26Sortm1Sor
Mdm4tm1Glo / Mdm4+
Mdm2tm2.1Glo / Mdm2+

Models

2 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Intestine polyp Intestine

observed

References: He XY, Cell Rep 2015 Nov 3;13(5):888-97

Leukocyte - Myelocyte (Granulocyte) tumor Intestine

observed

References: He XY, Cell Rep 2015 Nov 3;13(5):888-97