Strain SummaryC57BL/6-ApcMin/+ Lyz2tm1(cre)Ifo/+ Gt(ROSA)26Sortm1Sor Mdm2tm2.1Glo/+ Mdm4tm1Glo/+
Strain Name |
C57BL/6-ApcMin/+ Lyz2tm1(cre)Ifo/+ Gt(ROSA)26Sortm1Sor Mdm2tm2.1Glo/+ Mdm4tm1Glo/+ |
Strain Type(s) |
chemically induced mutation • targeted mutation (conditional) • targeted mutation (knock-in) • targeted mutation (knockout) • transgenic |
Strain Synonym(s) |
ApcMin/+; Rosa26; LysM-MM |
Description |
Compound mutant mice on a C57BL/6 genetic background with possible contribution from C57BL/6J, 129P2OlaHsd, and/or 129S7/SvEvBrd. |
Strain Genetics |
ApcMin / Apc+ |
Lyz2tm1(cre)Ifo / Lyz2+ | |
Gt(ROSA)26Sortm1Sor | |
Mdm4tm1Glo / Mdm4+ | |
Mdm2tm2.1Glo / Mdm2+ |
Frequency | ||||||||
---|---|---|---|---|---|---|---|---|
Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Intestine polyp | Intestine |
observed |
References: He XY, Cell Rep 2015 Nov 3;13(5):888-97 |
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Leukocyte - Myelocyte (Granulocyte) tumor | Intestine |
observed |
References: He XY, Cell Rep 2015 Nov 3;13(5):888-97 |