Strain SummaryFVB.B6-Mdm2tm2.1Glo/+
Strain Name |
FVB.B6-Mdm2tm2.1Glo/+ |
Strain Type(s) |
congenic • targeted mutation (conditional) |
Strain Synonym(s) |
control |
Description |
Heterozygous Mdm2tm2.1Glo mice on an FVB/N genetic background. These are control littermates after backcrossing for 5 generations from C57BL/6 to FVB/N. |
Strain Genetics |
Mdm2tm2.1Glo / Mdm2+ |
Frequency | ||||||||
---|---|---|---|---|---|---|---|---|
Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Intestine - Large Intestine - Colon adenocarcinoma | Intestine - Large Intestine - Colon | dextran sulfate sodium (DSS) ⋅ azoxymethane (AOM) |
observed |
References: He XY, Cell Rep 2015 Nov 3;13(5):888-97 |
||||
Intestine - Large Intestine - Colon dysplasia - high grade | Intestine - Large Intestine - Colon | dextran sulfate sodium (DSS) ⋅ azoxymethane (AOM) |
observed |
References: He XY, Cell Rep 2015 Nov 3;13(5):888-97 |
||||
Intestine - Large Intestine - Colon dysplasia - low grade | Intestine - Large Intestine - Colon | dextran sulfate sodium (DSS) ⋅ azoxymethane (AOM) |
observed |
References: He XY, Cell Rep 2015 Nov 3;13(5):888-97 |
||||
Intestine - Large Intestine - Colon tumor | Intestine - Large Intestine - Colon | dextran sulfate sodium (DSS) ⋅ azoxymethane (AOM) |
34 |
References: He XY, Cell Rep 2015 Nov 3;13(5):888-97 |
||||
Intestine - Large Intestine tumor | Intestine - Large Intestine | dextran sulfate sodium (DSS) ⋅ azoxymethane (AOM) |
observed |
References: He XY, Cell Rep 2015 Nov 3;13(5):888-97 |