Strain SummaryFVB.B6-Lyz2^tm1(cre)Ifo/+ Mdm2^tm2.1Glo/+ Mdm4^tm1Glo/+

Strain Name	FVB.B6-Lyz2^tm1(cre)Ifo/+ Mdm2^tm2.1Glo/+ Mdm4^tm1Glo/+
Strain Type(s)	congenic • targeted mutation (conditional) • targeted mutation (knock-in) • targeted mutation (knockout)
Strain Synonym(s)	LysM-MM
Description	Compound mutant mice on an FVB/N genetic background with possible contribution from C57BL/6J, 129P2OlaHsd, and/or 129S7/SvEvBrd. Mice were backcrossed for 5 generations from C57BL/6 to FVB/N.
Strain Genetics	List all models in MMHCdb carrying the Lyz2^tm1(cre)Ifo allele Lyz2^tm1(cre)Ifo / Lyz2⁺
	List all models in MMHCdb carrying the Mdm4^tm1Glo allele Mdm4^tm1Glo / Mdm4⁺
	List all models in MMHCdb carrying the Mdm2^tm2.1Glo allele Mdm2^tm2.1Glo / Mdm2⁺

Models
5 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Intestine - Large Intestine - Colon adenocarcinoma	Intestine - Large Intestine - Colon	dextran sulfate sodium (DSS) ⋅ azoxymethane (AOM)				0	References: He XY, Cell Rep 2015 Nov 3;13(5):888-97
Intestine - Large Intestine - Colon dysplasia - high grade	Intestine - Large Intestine - Colon	dextran sulfate sodium (DSS) ⋅ azoxymethane (AOM)				observed	References: He XY, Cell Rep 2015 Nov 3;13(5):888-97
Intestine - Large Intestine - Colon dysplasia - low grade	Intestine - Large Intestine - Colon	dextran sulfate sodium (DSS) ⋅ azoxymethane (AOM)				observed	References: He XY, Cell Rep 2015 Nov 3;13(5):888-97
Intestine - Large Intestine - Colon tumor	Intestine - Large Intestine - Colon	dextran sulfate sodium (DSS) ⋅ azoxymethane (AOM)				34	References: He XY, Cell Rep 2015 Nov 3;13(5):888-97
Intestine - Large Intestine tumor	Intestine - Large Intestine	dextran sulfate sodium (DSS) ⋅ azoxymethane (AOM)				observed	References: He XY, Cell Rep 2015 Nov 3;13(5):888-97

Models