Strain SummaryC57BL/6J-Nr1h4^tm1Gonz

Strain Name	C57BL/6J-Nr1h4^tm1Gonz
Strain Type(s)	targeted mutation (knockout)
Strain Synonym(s)	Fxr^-/-
Description	Homozygous Nr1h4 mutant mice on a predominantly C57BL/6J background with contribution from 129X1/SvJ.
Strain Genetics	List all models in MMHCdb carrying the Nr1h4^tm1Gonz allele Nr1h4^tm1Gonz / Nr1h4^tm1Gonz

Models
4 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Liver hepatocellular carcinoma	Liver					28	References: Kettner NM, Cancer Cell 2016 Dec 12;30(6):909-924
Liver hepatocellular carcinoma	Liver	jet-lag light cycle				61.29	References: Kettner NM, Cancer Cell 2016 Dec 12;30(6):909-924
Liver hyperplasia	Liver					100	References: Kettner NM, Cancer Cell 2016 Dec 12;30(6):909-924
Liver hyperplasia	Liver	jet-lag light cycle				100	References: Kettner NM, Cancer Cell 2016 Dec 12;30(6):909-924

Models