Strain SummaryB6.129-Krastm4.1Bbd/+

Strain Name

 B6.129-Krastm4.1Bbd/+

Strain Type(s)

 congenic  •  targeted mutation (knock-in)

Strain Synonym(s)

 B6-K-Ras+/V14I  •  B6 K-Ras+/V14I  •  B6-KRas+/V14I  •  BOX line  •  C57BL/6JOlaHsd-K-Ras+/V14I  •  C57BL/6J.OlaHsd-KRas+/V14I

Description

 Heterozygous mice. These mice had been backcrossed onto C57BL/6JOlaHsd. The genetic background also contained 129 (including at least 129X1/SvJ and/or 129S1/Sv).

Strain Genetics

 Krastm4.1Bbd / Kras+

Models

13 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Blood vessel hemangiosarcoma Blood vessel

0

0

0

References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17

Intestine - Small Intestine - Duodenum adenocarcinoma Intestine - Small Intestine - Duodenum

0

17

14

References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17

Intestine - Small Intestine - Duodenum adenoma Intestine - Small Intestine - Duodenum

100

0

14

References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17

Intestine adenocarcinoma Intestine

0

17

14

References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Leukocyte - Monocyte - Macrophage - Histiocyte

0

50

43

References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17

Leukocyte - Myelocyte (Granulocyte) hyperplasia Spleen

observed

References: Hernandez-Porras I, Rare Dis 2015;3(1):e1045169

Leukocyte lymphoma Leukocyte

100

67

71

References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17

Lung adenocarcinoma Lung

0

0

0

References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17

Lung adenoma Lung

0

0

0

References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17

Pancreas adenocarcinoma Pancreas

0

0

0

References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17

(Unspecified organ) adenocarcinoma (Unspecified organ)

0

17

14

References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17

(Unspecified organ) adenoma (Unspecified organ)

100

0

14

References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17

(Unspecified organ) tumor (Unspecified organ)

100

100

100

References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17