Strain Summary[not specified]-Krastm4Bbd/+ Polr2atm1(cre/ERT2)Bbd/+

Strain Name

[not specified]-Krastm4Bbd/+ Polr2atm1(cre/ERT2)Bbd/+

Strain Type(s)

targeted mutation (conditional)  •  targeted mutation (knock-in)

Strain Synonym(s)

K-Ras+/LSLV14I;RERT

Description

Double heterozygous mice. The genetic background of these mice was not specified but included at least 129 (129X1/SvJ and/or 129S1/Sv) and possibly some other strain(s).

Strain Genetics

Polr2atm1(cre/ERT2)Bbd / Polr2a+
Krastm4Bbd / Kras+

Models

1 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Lung tumor Lung tamoxifen (for inducing expression from mutant alleles)

0

References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17