Strain Summary[not specified]-Kras^tm1Bbd/+ Polr2a^{tm1(cre/ERT2)Bbd}/+

Strain Name	[not specified]-Kras^tm1Bbd/+ Polr2a^{tm1(cre/ERT2)Bbd}/+
Strain Type(s)	targeted mutation (conditional) • targeted mutation (knock-in)
Strain Synonym(s)	K-Ras^+/LSLG12Vgeo;RERT
Description	Double heterozygous mice. The genetic background of these mice was not specified but included at least 129 (129X1/SvJ and/or 129S1/Sv) and possibly some other strain(s).
Strain Genetics	List all models in MMHCdb carrying the Polr2a^{tm1(cre/ERT2)Bbd} allele Polr2a^{tm1(cre/ERT2)Bbd} / Polr2a⁺
	List all models in MMHCdb carrying the Kras^tm1Bbd allele Kras^tm1Bbd / Kras⁺

Models
3 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Lung adenocarcinoma	Lung	tamoxifen (for inducing expression from mutant alleles)				observed	References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17
Lung adenoma	Lung	tamoxifen (for inducing expression from mutant alleles)				observed	References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17
Lung tumor	Lung	tamoxifen (for inducing expression from mutant alleles)				100	References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17

Models