Strain Summary[not specified]-Krastm4.1Bbd/+

Strain Name

[not specified]-Krastm4.1Bbd/+

Strain Type(s)

targeted mutation (knock-in)

Strain Synonym(s)

K-Ras+/V14I  •  K-Ras+/V14I  •  +/V14I

Description

Heterozygous mice. The genetic background of these mice was not specified but included at least 129 (129X1/SvJ and/or 129S1/Sv) and possibly some other strain(s).

Strain Genetics

Krastm4.1Bbd / Kras+

Models

5 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Leukocyte - Lymphocyte - B-lymphocyte lymphoma Leukocyte - Lymphocyte - B-lymphocyte

observed

References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17

Lung adenoma Lung

observed

References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17

Pancreas adenocarcinoma - ductal Pancreas caerulein

0

References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17

Pancreas pancreatic intraepithelial neoplasia (PanIN) - high grade Pancreas caerulein

14.3 - 37.5

References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17

Pancreas pancreatic intraepithelial neoplasia (PanIN) - low grade Pancreas caerulein

14.3 - 62.5

References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17