Strain Summary[not specified]-Krastm4Bbd/+ Tg(Cela1-tTA)#Eps Tg(tetO-cre)3Jig
Strain Name |
[not specified]-Krastm4Bbd/+ Tg(Cela1-tTA)#Eps Tg(tetO-cre)3Jig |
Strain Type(s) |
targeted mutation (conditional) • transgenic |
Strain Synonym(s) |
K-Ras+/LSLV14I;Elas-tTA/tetO-Cre |
Description |
Compound mutant mice. The genetic background of these mice was not specified but included at least some FVB/N and some 129 (129X1/SvJ and/or 129S1/Sv) and possibly some other strain(s). |
Strain Genetics |
Tg(tetO-cre)3Jig |
Krastm4Bbd / Kras+ | |
Tg(Cela1-tTA)#Eps |
Frequency | ||||||||
---|---|---|---|---|---|---|---|---|
Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Pancreas adenocarcinoma - ductal | Pancreas | caerulein |
0 |
References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17 |
||||
Pancreas pancreatic intraepithelial neoplasia (PanIN) - high grade | Pancreas | caerulein |
10 - 11 |
References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17 |
||||
Pancreas pancreatic intraepithelial neoplasia (PanIN) - low grade | Pancreas | caerulein |
0 - 30 |
References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17 |