Strain Summary[not specified]-Cdkn2a^tm1Rdp Kras^tm4.1Bbd

Strain Name	[not specified]-Cdkn2a^tm1Rdp Kras^tm4.1Bbd
Strain Type(s)	targeted mutation (knock-in)
Strain Synonym(s)	BYP line • K-Ras^V14I;p16Ink4a/p19Arf^-/-
Description	Double homozygous mice. The genetic background of these mice was not specified but included at least 129 (129/Sv, 129X1/SvJ, and/or 129S1/Sv), C57BL/6J, SJL, and/or possibly some other strain(s).
Strain Genetics	List all models in MMHCdb carrying the Kras^tm4.1Bbd allele Kras^tm4.1Bbd / Kras^tm4.1Bbd
	List all models in MMHCdb carrying the Cdkn2a^tm1Rdp allele Cdkn2a^tm1Rdp / Cdkn2a^tm1Rdp

Models
12 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Connective tissue - Fibroblast fibrosarcoma	Connective tissue - Fibroblast		0	0	0		References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17
Leukocyte - Lymphocyte - B-lymphocyte lymphoma	Leukocyte - Lymphocyte - B-lymphocyte		0	33	12.5		References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma	Leukocyte - Monocyte - Macrophage - Histiocyte		80	100	87.5		References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma	Uterus - Uterine horn		observed				References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma	Spleen					observed	References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma	Pancreas					observed	References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma	Intestine - Small Intestine - Duodenum					observed	References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma	Liver					observed	References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma	Urinary bladder					observed	References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17
Leukocyte lymphoma	Leukocyte		20	67	37.5		References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17
Lymphatic vessel lymphangioma	Thymus		20	0	12.5		References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17
(Unspecified organ) tumor	(Unspecified organ)		100	100	100		References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17