Strain Summary[not specified]-Cdkn2atm1Rdp Krastm4.1Bbd/+

Strain Name

[not specified]-Cdkn2atm1Rdp Krastm4.1Bbd/+

Strain Type(s)

targeted mutation (knock-in)  •  targeted mutation (knockout)

Strain Synonym(s)

BYP line  •  K-Ras+/V14I;p16Ink4a/p19Arf-/-

Description

Compound mutant mice. The genetic background of these mice was not specified but included at least 129 (129/Sv, 129X1/SvJ, and/or 129S1/Sv), C57BL/6J, SJL, and/or possibly some other strain(s).

Strain Genetics

Krastm4.1Bbd / Kras+
Cdkn2atm1Rdp / Cdkn2atm1Rdp

Models

6 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Connective tissue - Fibroblast fibrosarcoma Connective tissue - Fibroblast

0

67

20

References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17

Leukocyte - Lymphocyte - B-lymphocyte lymphoma Leukocyte - Lymphocyte - B-lymphocyte

0

33

10

References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Leukocyte - Monocyte - Macrophage - Histiocyte

86

67

80

References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17

Leukocyte lymphoma Leukocyte

29

33

30

References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17

Mesodermal cell/mesoblast sarcoma - unclassified Mesodermal cell/mesoblast

14

0

10

References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17

(Unspecified organ) tumor (Unspecified organ)

100

100

100

References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17