Strain Summary[not specified]-Cdkn2atm1Rdp Krastm4.1Bbd/+
Strain Name |
[not specified]-Cdkn2atm1Rdp Krastm4.1Bbd/+ |
Strain Type(s) |
targeted mutation (knock-in) • targeted mutation (knockout) |
Strain Synonym(s) |
BYP line • K-Ras+/V14I;p16Ink4a/p19Arf-/- |
Description |
Compound mutant mice. The genetic background of these mice was not specified but included at least 129 (129/Sv, 129X1/SvJ, and/or 129S1/Sv), C57BL/6J, SJL, and/or possibly some other strain(s). |
Strain Genetics |
Krastm4.1Bbd / Kras+ |
Cdkn2atm1Rdp / Cdkn2atm1Rdp |
Frequency | ||||||||
---|---|---|---|---|---|---|---|---|
Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Connective tissue - Fibroblast fibrosarcoma | Connective tissue - Fibroblast |
0 |
67 |
20 |
References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17 |
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Leukocyte - Lymphocyte - B-lymphocyte lymphoma | Leukocyte - Lymphocyte - B-lymphocyte |
0 |
33 |
10 |
References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17 |
|||
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma | Leukocyte - Monocyte - Macrophage - Histiocyte |
86 |
67 |
80 |
References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17 |
|||
Leukocyte lymphoma | Leukocyte |
29 |
33 |
30 |
References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17 |
|||
Mesodermal cell/mesoblast sarcoma - unclassified | Mesodermal cell/mesoblast |
14 |
0 |
10 |
References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17 |
|||
(Unspecified organ) tumor | (Unspecified organ) |
100 |
100 |
100 |
References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17 |