Strain Summary[not specified]-Kras^tm4.1Bbd/+ Trp53^tm1Brd

Strain Name	[not specified]-Kras^tm4.1Bbd/+ Trp53^tm1Brd
Strain Type(s)	targeted mutation (knock-in) • targeted mutation (knockout)
Strain Synonym(s)	BOG line • K-Ras^+/V14I;Trp53^-/-
Description	Compound mutant mice. The genetic background of these mice was not specified but included at least 129 (129S7/SvEvBrd-Hprt⁺, 129X1/SvJ, and/or 129S1/Sv) and possibly some other strain(s).
Strain Genetics	List all models in MMHCdb carrying the Kras^tm4.1Bbd allele Kras^tm4.1Bbd / Kras⁺
	List all models in MMHCdb carrying the Trp53^tm1Brd allele Trp53^tm1Brd / Trp53^tm1Brd

Models
14 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Blood vessel hemangioma	Blood vessel		0	11	10		References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17
CNS - Brain tumor	CNS - Brain		0	11	10		References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17
Leukocyte - Lymphocyte - B-lymphocyte lymphoma	Leukocyte - Lymphocyte - B-lymphocyte		100	11	20		References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17
Leukocyte - Lymphocyte - T-lymphocyte lymphoma	Leukocyte - Lymphocyte - T-lymphocyte		0	11	10		References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17
Leukocyte lymphoma	Leukocyte		100	89	90		References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17
Leukocyte lymphoma	Spleen					observed	References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17
Leukocyte lymphoma	Kidney					observed	References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17
Leukocyte lymphoma	Lung					observed	References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17
Leukocyte lymphoma - lymphoblastic	Leukocyte		0		20 - 22		References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17
Leukocyte lymphoma - lymphoblastic	Thymus		0	11	10		References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17
Pancreas pancreatic intraepithelial neoplasia (PanIN)	Pancreas		0	11	10		References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17
(Unspecified organ) angiosarcoma	(Unspecified organ)		100	78	80		References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17
(Unspecified organ) angiosarcoma	Heart		0	22	20		References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17
(Unspecified organ) tumor	(Unspecified organ)		100	100	100		References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17