Strain SummaryC57BL/6-ApcMin/+ Insrtm1Khn Tg(Vil1-cre)997Gum

Strain Name

C57BL/6-ApcMin/+ Insrtm1Khn Tg(Vil1-cre)997Gum

Strain Type(s)

chemically induced mutation  •  targeted mutation (knock-in)  •  transgenic

Strain Synonym(s)

Vil1-cre Insrlox/lox ApcMin/+  •  VILIRKO-Min

Description

Heterozygous Apc, homozygous Insr mice carrying the transgene on a C57BL/6 background with contribution from 129S4/SvJae and SJL from the original ES cells.

Strain Genetics

ApcMin / Apc+
Tg(Vil1-cre)997Gum
Insrtm1Khn / Insrtm1Khn

Models

3 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Intestine - Small Intestine - Jejunum tumor Intestine - Small Intestine - Jejunum

observed

References: Wang X, Oncogene 2017 Aug 31;36(35):4987-4996

Intestine - Small Intestine tumor Intestine - Small Intestine low fat

observed

References: Wang X, Oncogene 2017 Aug 31;36(35):4987-4996

Intestine tumor Intestine

observed

References: Wang X, Oncogene 2017 Aug 31;36(35):4987-4996