Strain SummaryC57BL/6-Apc^Min/+ Insr^tm1Khn

Strain Name	C57BL/6-Apc^Min/+ Insr^tm1Khn
Strain Type(s)	chemically induced mutation • targeted mutation (knock-in)
Strain Synonym(s)	control • Insr^lox/lox Apc^Min/+
Description	Heterozygous Apc, homozygous Insr mice on a C57BL/6 background with contribution from 129S4/SvJae and SJL from the original ES cells. Littermate control mice without the "Vil1-cre" transgene.
Strain Genetics	List all models in MMHCdb carrying the Apc^Min allele Apc^Min / Apc⁺
	List all models in MMHCdb carrying the Insr^tm1Khn allele Insr^tm1Khn / Insr^tm1Khn

Models
3 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Intestine - Small Intestine - Jejunum tumor	Intestine - Small Intestine - Jejunum					observed	References: Wang X, Oncogene 2017 Aug 31;36(35):4987-4996
Intestine - Small Intestine tumor	Intestine - Small Intestine	low fat				observed	References: Wang X, Oncogene 2017 Aug 31;36(35):4987-4996
Intestine tumor	Intestine					observed	References: Wang X, Oncogene 2017 Aug 31;36(35):4987-4996

Models