Strain SummaryC57BL/6-ApcMin/+ Insrtm1Khn Tg(Cdh5-cre)7Mlia
Strain Name |
C57BL/6-ApcMin/+ Insrtm1Khn Tg(Cdh5-cre)7Mlia |
Strain Type(s) |
chemically induced mutation • targeted mutation (knock-in) • transgenic |
Strain Synonym(s) |
EndoIRKO-Min • Cdh5-cre Insrlox/lox ApcMin/+ |
Description |
Heterozygous Apc, homozygous Insr mice carrying the transgene on a C57BL/6 background with contribution from 129S4/SvJae and FVB/N from the original ES cells. |
Strain Genetics |
ApcMin / Apc+ |
Tg(Cdh5-cre)7Mlia | |
Insrtm1Khn / Insrtm1Khn |
Frequency | ||||||||
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Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Intestine - Small Intestine adenoma | Intestine - Small Intestine |
observed |
References: Wang X, Oncogene 2017 Aug 31;36(35):4987-4996 |
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Intestine - Small Intestine tumor | Intestine - Small Intestine |
observed |
References: Wang X, Oncogene 2017 Aug 31;36(35):4987-4996 |
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Intestine polyp | Intestine |
observed |
References: Wang X, Oncogene 2017 Aug 31;36(35):4987-4996 |
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Intestine tumor | Intestine |
observed |
References: Wang X, Oncogene 2017 Aug 31;36(35):4987-4996 |