Strain SummaryC57BL/6-ApcMin/+ Insrtm1Khn

Strain Name

C57BL/6-ApcMin/+ Insrtm1Khn

Strain Type(s)

chemically induced mutation  •  targeted mutation (knock-in)

Strain Synonym(s)

control  •  Insrlox/lox ApcMin/+

Description

Heterozygous Apc, homozygous Insr mice on a C57BL/6 background with contribution from 129S4/SvJae and FVB/N from the original ES cells. Littermate control mice without the "Chd5-cre" transgene.

Strain Genetics

ApcMin / Apc+
Insrtm1Khn / Insrtm1Khn

Models

1 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Intestine tumor Intestine

observed

References: Wang X, Oncogene 2017 Aug 31;36(35):4987-4996