Strain SummaryC57BL/6-ApcMin/+ Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo Tg(Cdh5-cre)7Mlia

Strain Name

C57BL/6-ApcMin/+ Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo Tg(Cdh5-cre)7Mlia

Strain Type(s)

chemically induced mutation  •  gene trapped  •  transgenic

Strain Synonym(s)

Cdh5-cre ApcMin/+ mTmG

Description

Heterozygous Apc mice carrying the transgenes on a C57BL/6 background with contribution from 129S4/SvJae and FVB/N from the original ES cells.

Strain Genetics

ApcMin / Apc+
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo / Gt(ROSA)26Sor
Tg(Cdh5-cre)7Mlia

Models

4 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Intestine - Small Intestine adenoma Intestine - Small Intestine

observed

References: Wang X, Oncogene 2017 Aug 31;36(35):4987-4996

Intestine - Small Intestine tumor Intestine - Small Intestine

observed

References: Wang X, Oncogene 2017 Aug 31;36(35):4987-4996

Intestine polyp Intestine

observed

References: Wang X, Oncogene 2017 Aug 31;36(35):4987-4996

Intestine tumor Intestine

observed

References: Wang X, Oncogene 2017 Aug 31;36(35):4987-4996