Strain SummarySTOCK E2f3^tm5(E2f1)Gle

Strain Name	STOCK E2f3^tm5(E2f1)Gle
Strain Type(s)	targeted mutation (knock-in)
Strain Synonym(s)	1^+/+3a^1KI/1KI • 3a^1KI/1KI • E2f1^+/+ E2f3a^1KI/1KI • E2f3a^1KI/1KI
Description	Homozygous mice. This STOCK background was a mixture of "FVB/NT" [Note: The "T" may be an erroneous indication of Taconic, lab code "Tac".], "129v/Sv", and "C57BL/Swiss".
Strain Genetics	List all models in MMHCdb carrying the E2f3^tm5(E2f1)Gle allele E2f3^tm5(E2f1)Gle / E2f3^tm5(E2f1)Gle

Models
5 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Liver adenoma	Liver			6.25		4.3	References: Kent LN, J Clin Invest 2017 Mar 01;127(3):830-842
Liver hepatocellular carcinoma	Liver		64	87.5		70	References: Kent LN, J Clin Invest 2017 Mar 01;127(3):830-842
Liver hepatocellular carcinoma	Liver	diethylnitrosamine (DEN)	80	100			References: Kent LN, J Clin Invest 2017 Mar 01;127(3):830-842
Liver tumor	Liver			94		observed	References: Kent LN, J Clin Invest 2017 Mar 01;127(3):830-842
Liver tumor	Liver	polyinosinic/polycytidylic acid (pIpC) (poly I:C)				observed	References: Kent LN, J Clin Invest 2017 Mar 01;127(3):830-842

Models