Strain SummarySTOCK E2f1tm1Meg/+ E2f3tm5(E2f1)Gle
Strain Name |
STOCK E2f1tm1Meg/+ E2f3tm5(E2f1)Gle |
Strain Type(s) |
targeted mutation (knock-in) • targeted mutation (knockout) |
Strain Synonym(s) |
1-/+3a1KI/1KI • E2f1-/+ E2f3a1KI/1KI |
Description |
Compound mutant mice. This STOCK background was a mixture of "FVB/NT" [Note: The "T" may be an erroneous indication of Taconic, lab code "Tac".], "129v/Sv", and "C57BL/Swiss". |
Strain Genetics |
E2f1tm1Meg / E2f1+ |
| E2f3tm5(E2f1)Gle / E2f3tm5(E2f1)Gle |
| Frequency | ||||||||
|---|---|---|---|---|---|---|---|---|
| Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
| Liver hepatocellular carcinoma | Liver |
22 |
References: Kent LN, J Clin Invest 2017 Mar 01;127(3):830-842 |
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