Strain SummaryB6;129-Scgb1a1tm1(icre)Fjd/? Stk11tm1Rdp

Strain Name

B6;129-Scgb1a1tm1(icre)Fjd/? Stk11tm1Rdp

Strain Type(s)

targeted mutation (conditional)  •  targeted mutation (knock-in)

Strain Synonym(s)

CCSPiCreLkb1f/f  •  CCSPiCreLkb1f/f  •  Lkb1d/d

Description

Compound mutant mice. The genetic background was stated to be "B6;129" (mixed C57BL/6 and 129), but it likely also contained some FVB & possibly some other strain(s). The substrains of 129 involved were at least 129X1/SvJ, 129S1/Sv, & 129S6/SvEvTac.

Strain Genetics

Scgb1a1tm1(icre)Fjd / Scgb1a1?
Stk11tm1Rdp / Stk11tm1Rdp

Models

17 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Lung adenocarcinoma Lung

37.5

References: Liu J, Nat Commun 2019 May 14;10(1):2148

2 pathology image(s)

Lung adenocarcinoma - mixed Lung

8.9

References: Liu J, Nat Commun 2019 May 14;10(1):2148

Lung adenocarcinoma - papillary Lung

25

References: Liu J, Nat Commun 2019 May 14;10(1):2148

Lung adenocarcinoma - solid Lung

1.8

References: Liu J, Nat Commun 2019 May 14;10(1):2148

Lung adenocarcinoma - squamous Lung

10.7

References: Liu J, Nat Commun 2019 May 14;10(1):2148

1 pathology image(s)

Lung adenoma Lung

8.9

References: Liu J, Nat Commun 2019 May 14;10(1):2148

Lung carcinoma - adenosquamous Lung

5.4

References: Liu J, Nat Commun 2019 May 14;10(1):2148

2 pathology image(s)

Lung carcinoma - large cell (LCC) Lung

observed

References: Liu J, Nat Commun 2019 May 14;10(1):2148

Lung carcinoma - large cell neuroendocrine Lung

observed

References: Liu J, Nat Commun 2019 May 14;10(1):2148

Lung hyperplasia Lung

observed

References: Liu J, Nat Commun 2019 May 14;10(1):2148

5 pathology image(s)

Lung hyperplasia - epithelial Lung

16.1

References: Liu J, Nat Commun 2019 May 14;10(1):2148

3 pathology image(s)

Lung lesion Lung

69.6

References: Liu J, Nat Commun 2019 May 14;10(1):2148

Lung metaplasia - squamous Lung

3.6

References: Liu J, Nat Commun 2019 May 14;10(1):2148

1 pathology image(s)

Lung preneoplastic lesion Lung

17.9

References: Liu J, Nat Commun 2019 May 14;10(1):2148

Lung squamous cell carcinoma Lung

16.1

References: Liu J, Nat Commun 2019 May 14;10(1):2148

5 pathology image(s)

Lung tumor Lung

58.9

References: Liu J, Nat Commun 2019 May 14;10(1):2148

Lung tumor - small cell - malignant Lung

observed

References: Liu J, Nat Commun 2019 May 14;10(1):2148