Strain SummaryB6;129-Scgb1a1tm1(icre)Fjd/? Stk11tm1Rdp
Strain Name |
B6;129-Scgb1a1tm1(icre)Fjd/? Stk11tm1Rdp |
Strain Type(s) |
targeted mutation (conditional) • targeted mutation (knock-in) |
Strain Synonym(s) |
CCSPiCreLkb1f/f • CCSPiCreLkb1f/f • Lkb1d/d |
Description |
Compound mutant mice. The genetic background was stated to be "B6;129" (mixed C57BL/6 and 129), but it likely also contained some FVB & possibly some other strain(s). The substrains of 129 involved were at least 129X1/SvJ, 129S1/Sv, & 129S6/SvEvTac. |
Strain Genetics |
Scgb1a1tm1(icre)Fjd / Scgb1a1? |
| Stk11tm1Rdp / Stk11tm1Rdp |
| Frequency | ||||||||
|---|---|---|---|---|---|---|---|---|
| Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
| Lung adenocarcinoma | Lung |
37.5 |
References: Liu J, Nat Commun 2019 May 14;10(1):2148 2 pathology image(s) |
|||||
| Lung adenocarcinoma - mixed | Lung |
8.9 |
References: Liu J, Nat Commun 2019 May 14;10(1):2148 |
|||||
| Lung adenocarcinoma - papillary | Lung |
25 |
References: Liu J, Nat Commun 2019 May 14;10(1):2148 |
|||||
| Lung adenocarcinoma - solid | Lung |
1.8 |
References: Liu J, Nat Commun 2019 May 14;10(1):2148 |
|||||
| Lung adenocarcinoma - squamous | Lung |
10.7 |
References: Liu J, Nat Commun 2019 May 14;10(1):2148 1 pathology image(s) |
|||||
| Lung adenoma | Lung |
8.9 |
References: Liu J, Nat Commun 2019 May 14;10(1):2148 |
|||||
| Lung carcinoma - adenosquamous | Lung |
5.4 |
References: Liu J, Nat Commun 2019 May 14;10(1):2148 2 pathology image(s) |
|||||
| Lung carcinoma - large cell (LCC) | Lung |
observed |
References: Liu J, Nat Commun 2019 May 14;10(1):2148 |
|||||
| Lung carcinoma - large cell neuroendocrine | Lung |
observed |
References: Liu J, Nat Commun 2019 May 14;10(1):2148 |
|||||
| Lung hyperplasia | Lung |
observed |
References: Liu J, Nat Commun 2019 May 14;10(1):2148 5 pathology image(s) |
|||||
| Lung hyperplasia - epithelial | Lung |
16.1 |
References: Liu J, Nat Commun 2019 May 14;10(1):2148 3 pathology image(s) |
|||||
| Lung lesion | Lung |
69.6 |
References: Liu J, Nat Commun 2019 May 14;10(1):2148 |
|||||
| Lung metaplasia - squamous | Lung |
3.6 |
References: Liu J, Nat Commun 2019 May 14;10(1):2148 1 pathology image(s) |
|||||
| Lung preneoplastic lesion | Lung |
17.9 |
References: Liu J, Nat Commun 2019 May 14;10(1):2148 |
|||||
| Lung squamous cell carcinoma | Lung |
16.1 |
References: Liu J, Nat Commun 2019 May 14;10(1):2148 5 pathology image(s) |
|||||
| Lung tumor | Lung |
58.9 |
References: Liu J, Nat Commun 2019 May 14;10(1):2148 |
|||||
| Lung tumor - small cell - malignant | Lung |
observed |
References: Liu J, Nat Commun 2019 May 14;10(1):2148 |
|||||