Strain SummaryB6;129-Scgb1a1tm1(icre)Fjd/? Trp53tm1Brn
Strain Name |
B6;129-Scgb1a1tm1(icre)Fjd/? Trp53tm1Brn |
Strain Type(s) |
targeted mutation (conditional) • targeted mutation (knock-in) |
Strain Synonym(s) |
CCSPiCrep53f/f • CCSPiCrep53f/f • P53d/d |
Description |
Compound mutant mice. The genetic background was stated to be "B6;129" (mixed C57BL/6 and 129), but it likely also contained some FVB & possibly some other strain(s). The substrains of 129 involved were at least 129X1/SvJ, 129S1/Sv, & 129P2/OlaHsd. |
Strain Genetics |
Scgb1a1tm1(icre)Fjd / Scgb1a1? |
| Trp53tm1Brn / Trp53tm1Brn |
| Frequency | ||||||||
|---|---|---|---|---|---|---|---|---|
| Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
| Lung adenocarcinoma | Lung |
10 |
References: Liu J, Nat Commun 2019 May 14;10(1):2148 1 pathology image(s) |
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| Lung adenocarcinoma - mixed | Lung |
0 |
References: Liu J, Nat Commun 2019 May 14;10(1):2148 |
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| Lung adenocarcinoma - papillary | Lung |
10 |
References: Liu J, Nat Commun 2019 May 14;10(1):2148 |
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| Lung adenocarcinoma - solid | Lung |
0 |
References: Liu J, Nat Commun 2019 May 14;10(1):2148 |
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| Lung adenocarcinoma - squamous | Lung |
0 |
References: Liu J, Nat Commun 2019 May 14;10(1):2148 |
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| Lung adenoma | Lung |
0 |
References: Liu J, Nat Commun 2019 May 14;10(1):2148 |
|||||
| Lung carcinoma - adenosquamous | Lung |
0 |
References: Liu J, Nat Commun 2019 May 14;10(1):2148 |
|||||
| Lung hyperplasia - epithelial | Lung |
10 |
References: Liu J, Nat Commun 2019 May 14;10(1):2148 |
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| Lung lesion | Lung |
20 |
References: Liu J, Nat Commun 2019 May 14;10(1):2148 |
|||||
| Lung metaplasia - squamous | Lung |
0 |
References: Liu J, Nat Commun 2019 May 14;10(1):2148 |
|||||
| Lung preneoplastic lesion | Lung |
10 |
References: Liu J, Nat Commun 2019 May 14;10(1):2148 |
|||||
| Lung squamous cell carcinoma | Lung |
0 |
References: Liu J, Nat Commun 2019 May 14;10(1):2148 |
|||||
| Lung tumor | Lung |
10 |
References: Liu J, Nat Commun 2019 May 14;10(1):2148 |
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