Strain SummaryB6;129-Mapk8tm1Rjd Mapk9tm1Flv Scgb1a1tm1(icre)Fjd/? Stk11tm1Rdp

Strain Name

 B6;129-Mapk8tm1Rjd Mapk9tm1Flv Scgb1a1tm1(icre)Fjd/? Stk11tm1Rdp

Strain Type(s)

 targeted mutation (conditional)  •  targeted mutation (knock-in)  •  targeted mutation (knockout)

Strain Synonym(s)

 CCSPiCreLkb1f/f Jnk1f/f Jnk2-/-  •  CCSPiCreLkb1f/f Jnk1f/f Jnk2-/-  •  CCSPiCreLkb1f/fJnk1f/fJnk2-/-  •  Lkb1d/dJnk1d/dJnk2-/-  •  Lkb1J1J2

Description

 Compound mutant mice. The genetic background was stated to be "B6;129" (mixed C57BL/6 and 129). it likely also contained some FVB & possibly others. The substrains of 129 involved were at least 129X1/SvJ, 129S1/Sv, 129S2/SvPas, & 129S6/SvEvTac.

Strain Genetics

 Mapk9tm1Flv / Mapk9tm1Flv
Mapk8tm1Rjd / Mapk8tm1Rjd
Scgb1a1tm1(icre)Fjd / Scgb1a1?
Stk11tm1Rdp / Stk11tm1Rdp

Models

24 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Lung adenocarcinoma Lung

22.2 - 41.7

References: Liu J, Nat Commun 2019 May 14;10(1):2148

4 pathology image(s)
Lung adenocarcinoma Lung anisomycin

10

References: Liu J, Nat Commun 2019 May 14;10(1):2148

Lung adenocarcinoma - mixed Lung

0

References: Liu J, Nat Commun 2019 May 14;10(1):2148

Lung adenocarcinoma - papillary Lung

0

References: Liu J, Nat Commun 2019 May 14;10(1):2148

Lung adenocarcinoma - solid Lung

0

References: Liu J, Nat Commun 2019 May 14;10(1):2148

Lung adenocarcinoma - squamous Lung

0 - 16.7

References: Liu J, Nat Commun 2019 May 14;10(1):2148

1 pathology image(s)
Lung adenocarcinoma - squamous Lung anisomycin

0

References: Liu J, Nat Commun 2019 May 14;10(1):2148

Lung adenoma Lung

0 - 8.3

References: Liu J, Nat Commun 2019 May 14;10(1):2148

Lung adenoma Lung anisomycin

30

References: Liu J, Nat Commun 2019 May 14;10(1):2148

Lung carcinoma - adenosquamous Lung

25 - 100

References: Liu J, Nat Commun 2019 May 14;10(1):2148

1 pathology image(s)
Lung carcinoma - adenosquamous Lung anisomycin

100

References: Liu J, Nat Commun 2019 May 14;10(1):2148

Lung hyperplasia Lung

observed

References: Liu J, Nat Commun 2019 May 14;10(1):2148

1 pathology image(s)
Lung hyperplasia - epithelial Lung

0 - 75

References: Liu J, Nat Commun 2019 May 14;10(1):2148

2 pathology image(s)
Lung hyperplasia - epithelial Lung anisomycin

0

References: Liu J, Nat Commun 2019 May 14;10(1):2148

Lung lesion Lung

100

References: Liu J, Nat Commun 2019 May 14;10(1):2148

Lung lesion Lung anisomycin

100

References: Liu J, Nat Commun 2019 May 14;10(1):2148

Lung metaplasia - squamous Lung

0 - 25

References: Liu J, Nat Commun 2019 May 14;10(1):2148

1 pathology image(s)
Lung metaplasia - squamous Lung anisomycin

0

References: Liu J, Nat Commun 2019 May 14;10(1):2148

Lung preneoplastic lesion Lung

0 - 75

References: Liu J, Nat Commun 2019 May 14;10(1):2148

1 pathology image(s)
Lung preneoplastic lesion Lung anisomycin

0

References: Liu J, Nat Commun 2019 May 14;10(1):2148

Lung squamous cell carcinoma Lung

33.3 - 100

References: Liu J, Nat Commun 2019 May 14;10(1):2148

1 pathology image(s)
Lung squamous cell carcinoma Lung anisomycin

50

References: Liu J, Nat Commun 2019 May 14;10(1):2148

Lung tumor Lung

58.3 - 100

References: Liu J, Nat Commun 2019 May 14;10(1):2148

Lung tumor Lung anisomycin

100

References: Liu J, Nat Commun 2019 May 14;10(1):2148