Strain Summary[not specified]-Cebpatm1Gonz Tg(Vil1-cre/ERT2)23Syr
Strain Name |
[not specified]-Cebpatm1Gonz Tg(Vil1-cre/ERT2)23Syr |
Strain Type(s) |
targeted mutation (knock-in) • transgenic |
Strain Synonym(s) |
C/EBPaFlox/Flox-VilinCreERT2 |
Description |
Homozygous Cebpa mice carrying the transgene on an unspecified background with contribution from 129X1/SvJ, C57BL/6 and DBA/2 from the original ES cells. |
Strain Genetics |
Cebpatm1Gonz / Cebpatm1Gonz |
Tg(Vil1-cre/ERT2)23Syr |
Frequency | ||||||||
---|---|---|---|---|---|---|---|---|
Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Intestine - Large Intestine - Colon - Distal adenoma | Intestine - Large Intestine - Colon - Distal | dextran sulfate sodium (DSS) ⋅ azoxymethane (AOM) ⋅ tamoxifen (for inducing expression from mutant alleles) |
100 |
References: Heuberger J, Life Sci Alliance 2019 Feb;2(1):e201800173 |
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Intestine - Large Intestine - Colon - Distal dysplasia - low grade | Intestine - Large Intestine - Colon - Distal | dextran sulfate sodium (DSS) ⋅ azoxymethane (AOM) ⋅ tamoxifen (for inducing expression from mutant alleles) |
100 |
References: Heuberger J, Life Sci Alliance 2019 Feb;2(1):e201800173 |
||||
Intestine - Large Intestine - Colon adenoma | Intestine - Large Intestine - Colon | dextran sulfate sodium (DSS) ⋅ azoxymethane (AOM) ⋅ tamoxifen (for inducing expression from mutant alleles) |
observed |
References: Heuberger J, Life Sci Alliance 2019 Feb;2(1):e201800173 |
||||
Intestine - Large Intestine - Colon lesion | Intestine - Large Intestine - Colon | dextran sulfate sodium (DSS) ⋅ azoxymethane (AOM) ⋅ tamoxifen (for inducing expression from mutant alleles) |
observed |
References: Heuberger J, Life Sci Alliance 2019 Feb;2(1):e201800173 |