Strain Summary[not specified]-Cebpa^tm1Gonz

Strain Name	[not specified]-Cebpa^tm1Gonz
Strain Type(s)	targeted mutation (conditional)
Strain Synonym(s)	C/EBPa^Flox/Flox
Description	Homozygous Cebpa mice on an unspecified background with contribution from 129X1/SvJ, C57BL/6 and DBA/2 from the original ES cells.
Strain Genetics	List all models in MMHCdb carrying the Cebpa^tm1Gonz allele Cebpa^tm1Gonz / Cebpa^tm1Gonz

Models
4 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Intestine - Large Intestine - Colon - Distal adenoma	Intestine - Large Intestine - Colon - Distal	dextran sulfate sodium (DSS) ⋅ azoxymethane (AOM) ⋅ tamoxifen (for inducing expression from mutant alleles)				100	References: Heuberger J, Life Sci Alliance 2019 Feb;2(1):e201800173
Intestine - Large Intestine - Colon - Distal dysplasia - low grade	Intestine - Large Intestine - Colon - Distal	dextran sulfate sodium (DSS) ⋅ azoxymethane (AOM) ⋅ tamoxifen (for inducing expression from mutant alleles)				100	References: Heuberger J, Life Sci Alliance 2019 Feb;2(1):e201800173
Intestine - Large Intestine - Colon adenoma	Intestine - Large Intestine - Colon	dextran sulfate sodium (DSS) ⋅ azoxymethane (AOM) ⋅ tamoxifen (for inducing expression from mutant alleles)				observed	References: Heuberger J, Life Sci Alliance 2019 Feb;2(1):e201800173
Intestine - Large Intestine - Colon lesion	Intestine - Large Intestine - Colon	dextran sulfate sodium (DSS) ⋅ azoxymethane (AOM) ⋅ tamoxifen (for inducing expression from mutant alleles)				observed	References: Heuberger J, Life Sci Alliance 2019 Feb;2(1):e201800173

Models