Strain SummaryC57BL/6-Apc^Min/+ Defa4^{tm1.1(cre)Fya}/+ Gt(ROSA)26Sor^{tm4(ACTB-tdTomato,-EGFP)Luo}

Strain Name	C57BL/6-Apc^Min/+ Defa4^{tm1.1(cre)Fya}/+ Gt(ROSA)26Sor^{tm4(ACTB-tdTomato,-EGFP)Luo}
Strain Type(s)	chemically induced mutation • targeted mutation (conditional) • targeted mutation (knock-in)
Strain Synonym(s)	Defa4-Cre, mTmG, Apc^Min
Description	Heterozygous Apc, Defa4, Gt(ROSA) mice on a C57BL/6 background with contribution from C57BL/6J, 129X1/SvJ and 129S1/Sv. All strains involved in creating this strain were backcrossed at least 7 times to C57BL/6 except Apc^Min.
Strain Genetics	List all models in MMHCdb carrying the Apc^Min allele Apc^Min / Apc⁺
	List all models in MMHCdb carrying the Gt(ROSA)26Sor^{tm4(ACTB-tdTomato,-EGFP)Luo} allele List all models in MMHCdb carrying the Gt(ROSA)26Sor allele Gt(ROSA)26Sor^{tm4(ACTB-tdTomato,-EGFP)Luo} / Gt(ROSA)26Sor
	List all models in MMHCdb carrying the Defa4^{tm1.1(cre)Fya} allele Defa4^{tm1.1(cre)Fya} / Defa4⁺

Models
6 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Intestine - Large Intestine - Colon adenoma	Intestine - Large Intestine - Colon				observed		References: Chen Q, Life Sci Alliance 2021 Mar;4(3):
Intestine - Small Intestine - Paneth Cell adenoma	Intestine - Small Intestine - Paneth Cell				observed		References: Chen Q, Life Sci Alliance 2021 Mar;4(3):
Intestine - Small Intestine - Paneth Cell lesion - neoplastic	Intestine - Small Intestine - Paneth Cell				observed		References: Chen Q, Life Sci Alliance 2021 Mar;4(3):
Intestine - Small Intestine adenoma	Intestine - Small Intestine				observed		References: Chen Q, Life Sci Alliance 2021 Mar;4(3):
Intestine adenoma	Intestine				observed		References: Chen Q, Life Sci Alliance 2021 Mar;4(3):
Intestine lesion - neoplastic	Intestine				observed		References: Chen Q, Life Sci Alliance 2021 Mar;4(3):

Models