Strain SummaryC57BL/6-Apc^Min/+ Defa4^{tm1.1(cre)Fya}/+ Gt(ROSA)26Sor^tm1(DTA)Lky

Strain Name	C57BL/6-Apc^Min/+ Defa4^{tm1.1(cre)Fya}/+ Gt(ROSA)26Sor^tm1(DTA)Lky
Strain Type(s)	chemically induced mutation • targeted mutation (conditional) • targeted mutation (knock-in)
Strain Synonym(s)	Apc^Min, PC^Del
Description	Heterozygous Apc, Defa4, Gt(ROSA) mice on a C57BL/6 background with contribution from C57BL/6J, and 129P2/OlaHsd. All strains involved in creating this strain were backcrossed at least 7 times to C57BL/6 except Apc^Min.
Strain Genetics	List all models in MMHCdb carrying the Apc^Min allele Apc^Min / Apc⁺
	List all models in MMHCdb carrying the Gt(ROSA)26Sor^tm1(DTA)Lky allele List all models in MMHCdb carrying the Gt(ROSA)26Sor allele Gt(ROSA)26Sor^tm1(DTA)Lky / Gt(ROSA)26Sor
	List all models in MMHCdb carrying the Defa4^{tm1.1(cre)Fya} allele Defa4^{tm1.1(cre)Fya} / Defa4⁺

Models
2 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Intestine - Large Intestine - Colon adenoma	Intestine - Large Intestine - Colon				100		References: Chen Q, Life Sci Alliance 2021 Mar;4(3):
Intestine - Small Intestine adenoma	Intestine - Small Intestine				observed - 100		References: Chen Q, Life Sci Alliance 2021 Mar;4(3):

Models