Strain SummaryC57BL/6-ApcMin/+ Defa4tm1.1(cre)Fya/+ Wnt3tm2Amc/+
Strain Name |
C57BL/6-ApcMin/+ Defa4tm1.1(cre)Fya/+ Wnt3tm2Amc/+ |
Strain Type(s) |
chemically induced mutation • targeted mutation (conditional) • targeted mutation (knock-in) |
Strain Synonym(s) |
C57BL/6-ApcMin/+ Defa4tm1.1(cre)Fya/+ Wnt3atm2Amc/+ • ApcMin PC-Wnt3+/? |
Description |
Heterozygous Apc, Defa4, Wnt3 mice on a C57BL/6 background with contribution from C57BL/6J, 129X1/SvJ and 129S1/Sv. All strains involved in creating this strain were backcrossed at least 7 times to C57BL/6 except ApcMin. |
Strain Genetics |
ApcMin / Apc+ |
Defa4tm1.1(cre)Fya / Defa4+ | |
Wnt3tm2Amc / Wnt3+ |
Frequency | ||||||||
---|---|---|---|---|---|---|---|---|
Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Intestine - Large Intestine - Colon adenoma | Intestine - Large Intestine - Colon |
100 |
References: Chen Q, Life Sci Alliance 2021 Mar;4(3): |
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Intestine - Small Intestine adenoma | Intestine - Small Intestine |
100 |
References: Chen Q, Life Sci Alliance 2021 Mar;4(3): |