Strain SummaryC57BL/6-ApcMin/+ Defa4tm1.1(cre)Fya/+ Wnt3tm2Amc/+

Strain Name

C57BL/6-ApcMin/+ Defa4tm1.1(cre)Fya/+ Wnt3tm2Amc/+

Strain Type(s)

chemically induced mutation  •  targeted mutation (conditional)  •  targeted mutation (knock-in)

Strain Synonym(s)

C57BL/6-ApcMin/+ Defa4tm1.1(cre)Fya/+ Wnt3atm2Amc/+  •  ApcMin PC-Wnt3+/?

Description

Heterozygous Apc, Defa4, Wnt3 mice on a C57BL/6 background with contribution from C57BL/6J, 129X1/SvJ and 129S1/Sv. All strains involved in creating this strain were backcrossed at least 7 times to C57BL/6 except ApcMin.

Strain Genetics

ApcMin / Apc+
Defa4tm1.1(cre)Fya / Defa4+
Wnt3tm2Amc / Wnt3+

Models

2 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Intestine - Large Intestine - Colon adenoma Intestine - Large Intestine - Colon

100

References: Chen Q, Life Sci Alliance 2021 Mar;4(3):

Intestine - Small Intestine adenoma Intestine - Small Intestine

100

References: Chen Q, Life Sci Alliance 2021 Mar;4(3):