Strain SummaryC57BL/6J-Apc^Min/+ Tspan6^tm2Vlcg

Strain Name	C57BL/6J-Apc^Min/+ Tspan6^tm2Vlcg
Strain Type(s)	chemically induced mutation • targeted mutation (knockout)
Strain Synonym(s)	APC^min/+Tspan6^?/?
Description	Heterozygous Apc, homozygous Tspan6 mice on a C57BL/6 background with contribution from C57BL/6J anfd 129P2/OlaHsd.
Strain Genetics	List all models in MMHCdb carrying the Apc^Min allele Apc^Min / Apc⁺
	List all models in MMHCdb carrying the Tspan6^tm2Vlcg allele Tspan6^tm2Vlcg / Tspan6^tm2Vlcg

Models
11 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Intestine - Large Intestine - Colon adenoma	Intestine - Large Intestine - Colon					39.13	References: Andrijes R, Proc Natl Acad Sci U S A 2021 Sep 28;118(39):
Intestine - Large Intestine - Colon dysplasia - high grade	Intestine - Large Intestine - Colon					39.13	References: Andrijes R, Proc Natl Acad Sci U S A 2021 Sep 28;118(39):
Intestine - Large Intestine - Colon dysplasia - low grade	Intestine - Large Intestine - Colon					65.22	References: Andrijes R, Proc Natl Acad Sci U S A 2021 Sep 28;118(39):
Intestine - Small Intestine adenoma	Intestine - Small Intestine					43.48 - 86.96	References: Andrijes R, Proc Natl Acad Sci U S A 2021 Sep 28;118(39):
Intestine - Small Intestine dysplasia - high grade	Intestine - Small Intestine					43.48	References: Andrijes R, Proc Natl Acad Sci U S A 2021 Sep 28;118(39):
Intestine - Small Intestine dysplasia - low grade	Intestine - Small Intestine					86.96	References: Andrijes R, Proc Natl Acad Sci U S A 2021 Sep 28;118(39):
Intestine - Small Intestine lesion	Intestine - Small Intestine					0	References: Andrijes R, Proc Natl Acad Sci U S A 2021 Sep 28;118(39):
Intestine - Small Intestine lesion - malignant	Intestine - Small Intestine					observed	References: Andrijes R, Proc Natl Acad Sci U S A 2021 Sep 28;118(39):
Intestine lesion	Intestine					observed	References: Andrijes R, Proc Natl Acad Sci U S A 2021 Sep 28;118(39):
Intestine polyp	Intestine					observed - 100	References: Andrijes R, Proc Natl Acad Sci U S A 2021 Sep 28;118(39):
Intestine tumor	Intestine					observed	References: Andrijes R, Proc Natl Acad Sci U S A 2021 Sep 28;118(39):