Strain Summary(DBA/1J x C57BL/6)F1-Trp53tm3.1Glo/+
Strain Name |
(DBA/1J x C57BL/6)F1-Trp53tm3.1Glo/+ |
Strain Type(s) |
hybrid • targeted mutation (knock-in) |
Strain Synonym(s) |
DBA • DBA C57Bl/6 F-1 hybrid Trp53R172H heterozygote • DBA C57Bl/6 F-1 p53 R172H • DBA F-1 |
Description |
Heterozygous mice. The genetic background of these mice was (DBA/1J x C57BL/6)F1 hybrid with a small contribution from 129S7/SvEvBrd-Hprt+ from the original generation of the mutant allele. |
Strain Genetics |
Trp53tm3.1Glo / Trp53+ |
Frequency | ||||||||
---|---|---|---|---|---|---|---|---|
Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Adipose tissue tumor | Adipose tissue |
4 |
References: Chan CS, Life Sci Alliance 2021 Mar;4(3): |
|||||
Blood vessel hemangioma | Blood vessel |
4 |
References: Chan CS, Life Sci Alliance 2021 Mar;4(3): |
|||||
Bone osteosarcoma | Bone |
4 |
References: Chan CS, Life Sci Alliance 2021 Mar;4(3): |
|||||
Leukocyte lesion | Leukocyte |
21 |
References: Chan CS, Life Sci Alliance 2021 Mar;4(3): |
|||||
Mesodermal cell/mesoblast sarcoma | Mesodermal cell/mesoblast |
0 |
References: Chan CS, Life Sci Alliance 2021 Mar;4(3): |
|||||
(Unspecified organ) adenocarcinoma | (Unspecified organ) |
7 |
References: Chan CS, Life Sci Alliance 2021 Mar;4(3): |
|||||
(Unspecified organ) carcinoma | (Unspecified organ) |
0 |
References: Chan CS, Life Sci Alliance 2021 Mar;4(3): |
|||||
(Unspecified organ) tumor | (Unspecified organ) |
45 |
47 |
4 - 46 |
References: Chan CS, Life Sci Alliance 2021 Mar;4(3): |