Strain Summary(NOD/ShiLtJ x C57BL/6)F1-Trp53tm3.1Glo/+
Strain Name |
(NOD/ShiLtJ x C57BL/6)F1-Trp53tm3.1Glo/+ |
Strain Type(s) |
hybrid • targeted mutation (knock-in) |
Strain Synonym(s) |
NOD • NOD C57Bl/6 F-1 hybrid Trp53R172H heterozygote • NOD C57Bl/6 F-1 p53 R172H • NOD F-1 |
Description |
Heterozygous mice. The genetic background of these mice was (NOD/ShiLtJ x C57BL/6)F1 hybrid with a small contribution from 129S7/SvEvBrd-Hprt+ from the original generation of the mutant allele. |
Strain Genetics |
Trp53tm3.1Glo / Trp53+ |
Frequency | ||||||||
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Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Adipose tissue tumor | Adipose tissue |
0 |
References: Chan CS, Life Sci Alliance 2021 Mar;4(3): |
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Blood vessel hemangioma | Blood vessel |
3 |
References: Chan CS, Life Sci Alliance 2021 Mar;4(3): |
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Bone osteosarcoma | Bone |
16 |
References: Chan CS, Life Sci Alliance 2021 Mar;4(3): |
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Leukocyte lesion | Leukocyte |
24 |
References: Chan CS, Life Sci Alliance 2021 Mar;4(3): |
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Mesodermal cell/mesoblast sarcoma | Mesodermal cell/mesoblast |
8 |
References: Chan CS, Life Sci Alliance 2021 Mar;4(3): |
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(Unspecified organ) adenocarcinoma | (Unspecified organ) |
3 |
References: Chan CS, Life Sci Alliance 2021 Mar;4(3): |
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(Unspecified organ) carcinoma | (Unspecified organ) |
1 |
References: Chan CS, Life Sci Alliance 2021 Mar;4(3): |
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(Unspecified organ) tumor | (Unspecified organ) |
65 |
49 |
1 - 57 |
References: Chan CS, Life Sci Alliance 2021 Mar;4(3): |
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(Unspecified organ) tumor - malignant | (Unspecified organ) |
69 |
References: Chan CS, Life Sci Alliance 2021 Mar;4(3): |