Model DetailsThyroid gland - Medulla - C cell carcinoma

Model Name

 Thyroid gland - Medulla - C cell carcinoma

Strain
[not specified]-Calcatm1.1(cre/ERT2)Ptch/+ Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/+ Rb1tm2Brn Trp53tm1Brn

Tumor Inducing Agent(s)

 Genetic Modification : tamoxifen (for inducing expression from mutant alleles)

Tumor Synonyms

 medullary thyroid carcinoma  •  medullary thyroid tumor  •  thyroid tumor

Strain Synonyms

 CGRPCreER/+; p53f/f; Rbf/f; Rosa26mTmG/+  •  p53-/-; Rb-/-; ROSA26mTmG/+
Organ Affected Sex Frequency Age Of Detection Additional Information Expand all Collapse all Reference
Thyroid gland - Medulla - C cell Mixed Population

100%

 7-8 months
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

  • Age of Onset

    ~3-5 months

  • Pathology Reports
Song H, J Biol Chem 2017 Mar 3;292(9):3888-3899