Model DetailsLeukocyte - Myelocyte (Granulocyte) hyperplasia(Spleen)
Model Name |
Leukocyte - Myelocyte (Granulocyte) hyperplasia (Spleen) | Strain |
B6;129-Krastm4.1Bbd/+ |
Tumor Inducing Agent(s) |
Chemical/Drug : PD0325901 (MEK inhibitor) |
Tumor Synonyms |
myeloproliferative disease (MPD) • splenomegaly |
Strain Synonyms |
K-Ras+/V14I • AVB line |
| Organ Affected | Sex | Frequency | Age Of Detection | Additional Information Expand all Collapse all | Reference |
|---|---|---|---|---|---|
| Spleen | Male |
100% (10 of 10 mice) |
4 months |
|
Hernandez-Porras I, Proc Natl Acad Sci U S A 2014 Nov 18;111(46):16395-400 |
| Spleen | Unspecified |
100% (12 of 12 mice) |
63 days |
|
Hernandez-Porras I, Proc Natl Acad Sci U S A 2014 Nov 18;111(46):16395-400 |
| Spleen | Unspecified |
100% (11 of 11 mice) |
5 months |
|
Hernandez-Porras I, Proc Natl Acad Sci U S A 2014 Nov 18;111(46):16395-400 |