Reference SummaryStrong LC, Yale J Biol Med 1952;25():34-43

Title

 Differences in response among mice of fifteen inbred strains to the subcutaneous injection of methylcholanthrene

Authors

 Strong LC

Journal

 Yale J Biol Med

Volume

 25

Issue

Year

 1952

Pages

 34-43

Abstract

Links

 J:22766 – MGI References
13006401 – National Library of Medicine/PubMed

Strain Notes

Strain Note
CBAN The CBAN strain was generated by mating a CBA female with a N male. Mice in these experiments were of generations F24-F30.

Models
Strain Model Name Treatment Agent(s) Organ Affected Frequency Model Details
CHI Connective tissue - Fibroblast fibrosarcoma
  • methylcholanthrene (MCA)
 Connective tissue - Fibroblast

76 - 89
A Connective tissue - Fibroblast fibrosarcoma
  • methylcholanthrene (MCA)
 Connective tissue - Fibroblast

72 - 79
C57 Connective tissue - Fibroblast fibrosarcoma
  • methylcholanthrene (MCA)
 Connective tissue - Fibroblast

77 - 84
C Connective tissue - Fibroblast fibrosarcoma
  • methylcholanthrene (MCA)
 Connective tissue - Fibroblast

67 - 73
CBA Connective tissue - Fibroblast fibrosarcoma
  • methylcholanthrene (MCA)
 Connective tissue - Fibroblast

77 - 79
CBAN Connective tissue - Fibroblast fibrosarcoma
  • methylcholanthrene (MCA)
 Connective tissue - Fibroblast

58 - 61
C3H Connective tissue - Fibroblast fibrosarcoma
  • methylcholanthrene (MCA)
 Connective tissue - Fibroblast

87.5 - 90
C121 Connective tissue - Fibroblast fibrosarcoma
  • methylcholanthrene (MCA)
 Connective tissue - Fibroblast

78 - 81
F Connective tissue - Fibroblast fibrosarcoma
  • methylcholanthrene (MCA)
 Connective tissue - Fibroblast

21 - 32
FC Connective tissue - Fibroblast fibrosarcoma
  • methylcholanthrene (MCA)
 Connective tissue - Fibroblast

64 - 71
I Connective tissue - Fibroblast fibrosarcoma
  • methylcholanthrene (MCA)
 Connective tissue - Fibroblast

14 - 24
JK Connective tissue - Fibroblast fibrosarcoma
  • methylcholanthrene (MCA)
 Connective tissue - Fibroblast

31 - 68
JKL Connective tissue - Fibroblast fibrosarcoma
  • methylcholanthrene (MCA)
 Connective tissue - Fibroblast

63 - 67
L Connective tissue - Fibroblast fibrosarcoma
  • methylcholanthrene (MCA)
 Connective tissue - Fibroblast

80 - 85
N Connective tissue - Fibroblast fibrosarcoma
  • methylcholanthrene (MCA)
 Connective tissue - Fibroblast

60 - 66
F Leukocyte - Lymphocyte leukemia - lymphocytic Leukocyte - Lymphocyte

high
F Leukocyte - Myelocyte (Granulocyte) leukemia - myelocytic Leukocyte - Myelocyte (Granulocyte)

high
CBA Liver hepatoma Liver

observed
C3H Liver hepatoma Liver

observed
A Lung adenoma Lung

observed
JK Lung adenoma Lung

observed
A Mammary gland adenocarcinoma Mammary gland

high
CBA Mammary gland adenocarcinoma Mammary gland

high
C3H Mammary gland adenocarcinoma Mammary gland

high
I Stomach - Glandular hyperplasia - adenomatous Stomach - Glandular

high
N (Unspecified organ) tumor (Unspecified organ)

0
CBA (Unspecified organ) tumor (Unspecified organ)

very low
I (Unspecified organ) tumor (Unspecified organ)

very low
JK (Unspecified organ) tumor (Unspecified organ)

very low
L (Unspecified organ) tumor (Unspecified organ)

very low