Strain SummaryA

Strain Name

 A

Strain Type(s)

 inbred

Strain Synonym(s)

 strain A  •  Strong's albino

Description

 Substrain not specified.

Strain Links

 • Festing's List of Inbred Strains

Models

78 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Adrenal gland - Cortex tumor Adrenal gland - Cortex

observed

References: Murphy ED, 1966;():521-62

Blood vessel hemangioendothelioma Blood vessel 4-o-tolylazo-o-toluidine (2-amino-5-azotoluene)

observed

References: Deringer MK, J Natl Cancer Inst 1956;17(4):533-9

Connective tissue - Fibroblast fibrosarcoma Connective tissue - Fibroblast methylcholanthrene (MCA)

72

79

References: Strong LC, Yale J Biol Med 1952;25():34-43

Leukocyte - Lymphocyte leukemia - lymphocytic Leukocyte - Lymphocyte

10.0 - 43.0

References: Festing MFW, Mouse Genome 1996;94(3):523-677

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytoma Leukocyte - Monocyte - Macrophage - Histiocyte

observed

observed

References: Staats J, Companion to Mouse News Lett No. 33 1965;():

Leukocyte leukemia Leukocyte BALB/Tennant leukemia virus

observed

References: Festing MFW, Mouse Genome 1996;94(3):523-677

Lung - Alveolus tumor Lung - Alveolus

high

References: Murphy ED, 1966;():521-62

Lung adenoma Lung

observed

observed

observed - high

References: Festing MFW, Mouse Genome 1996;94(3):523-677   ⋅   Shimkin MB, Adv Cancer Res 1975;21():1-58   ⋅   Strong LC, Yale J Biol Med 1952;25():34-43

Lung adenoma Lung urethane (ethyl carbamate)

observed

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung carcinoma Lung

observed

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105

Lung tumor Lung

low - high

observed

0 - 77

observed - 100

References: Festing MFW, Mouse Genome 1996;94(3):523-677   ⋅   Heston WE, 1963;():247-68   ⋅   Heston WE, J Natl Cancer Inst 1942;3():79-82   ⋅   International Nomenclature Committee, Cancer Res 1952 Aug;12(8):602-13   ⋅   Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6   ⋅   Murphy ED, 1966;():521-62   ⋅   Shimkin MB, Adv Cancer Res 1975;21():1-58   ⋅   Staats J, Companion to Mouse News Lett No. 37 1967;():

Lung tumor Lung urethane (ethyl carbamate)

100

observed - 100

References: Festing MFW, Mouse Genome 1996;94(3):523-677   ⋅   Shimkin MB, Adv Cancer Res 1975;21():1-58   ⋅   Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung dimethylbenzanthracene (DMBA)

observed

References: Festing MFW, Mouse Genome 1996;94(3):523-677

Lung tumor Lung nitrogen mustard (HN2)

very high

References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung 3-methylcholanthrene (MCA) (3-MC)

observed

observed - 100

References: Shimkin MB, Adv Cancer Res 1975;21():1-58   ⋅   Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung dibenz[a,h]anthracene (1,2,5,6-dibenzanthracene)

very high - 100

References: Shimkin MB, Adv Cancer Res 1975;21():1-58   ⋅   Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung 7H-dibenzo[c,g]carbazole (3,4,5,6-dibenzocarbazole) (DBC)

high - 100

References: Shimkin MB, Adv Cancer Res 1975;21():1-58   ⋅   Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung 3,4-benzopyrene (benzo[a]pyrene)

high - 100

References: Shimkin MB, Adv Cancer Res 1975;21():1-58   ⋅   Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung dibenz[a,j]aceanthrylene (15,16-benzdehydrocholanthrene)

high - 90

References: Shimkin MB, Adv Cancer Res 1975;21():1-58   ⋅   Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung dibenz[a,h]acridine (1,2,5,6-dibenzacridine)

high - 92

References: Shimkin MB, Adv Cancer Res 1975;21():1-58   ⋅   Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung 8-methylbenzo[c]phenanthrene (2-methyl-3,4-benzophenanthrene)

observed - 55

References: Shimkin MB, Adv Cancer Res 1975;21():1-58   ⋅   Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung 7-methylbenzo[a]pyrene (4'-methyl-3,4-benzopyrene)

observed - 50

References: Shimkin MB, Adv Cancer Res 1975;21():1-58   ⋅   Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung 5-methoxy-7-propylbenz[a]-anthracene (3-methoxy-10-propyl-1,2-benzanthracene)

observed - 10

References: Shimkin MB, Adv Cancer Res 1975;21():1-58   ⋅   Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung benz[a]anthracene (1,2-benzanthracene)

observed - 18

References: Shimkin MB, Adv Cancer Res 1975;21():1-58   ⋅   Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung 4-o-tolylazo-o-toluidine (2-amino-5-azotoluene)

high - 100

References: Shimkin MB, Adv Cancer Res 1975;21():1-58   ⋅   Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung 2-acetylaminofluorene (AAF)

95

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung N-hydroxy-2-acetylaminofluorene

84

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung aflatoxin B1 (AFB1) (AFB1)

100

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung DDT

34

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung triethylene melamine (TEM)

86

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung thioTEPA (thio-TEPA) (TESPA)

80

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung estradiol mustard

100

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung beta-deoxythioguanosine

71

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung isophosphamide

83

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung 1-propanol-3,3'-imino dimethanesulfonate

67

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung phenesterin

100

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung imidazole mustard

85

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung aminopterin

30

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung Adriamycin

25

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung potassium arsenite

37.5

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung emetine

37.5

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung stilbamidine

24

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung cortisone

29

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung phenazopyridine

33

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung phenformin

26

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung acronycine

29

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung tolbutamide

40

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung cigarette smoke

64

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung isopropyl carbamate

90

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung propyl carbamate

63

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung trichloroethyl carbamate

42

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung methyl carbamate

15

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung butyl carbamate

12

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung isoamyl carbamate

13

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung chloroethyl carbamate

15

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung N-methylurethane

91

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung N-dimethylurethane

81

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung N-ethylurethane

86

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung N-diethylurethane

93

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung N-propylurethane

100

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung N-dipropylurethane

95

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung N-isopropylurethane

100

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung N-disopropylurethane

79

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung N-butylurethane

32

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung N-dibutylurethane

20

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung N-diphenylurethane

16

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung methylene diurethane

100

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung ethylene diurethane

98

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung ethylidene diurethane

100

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Mammary gland adenocarcinoma Mammary gland

high

References: Strong LC, Yale J Biol Med 1952;25():34-43

Mammary gland carcinoma Mammary gland MMTV - mouse mammary tumor virus

observed

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105

Mammary gland tumor Mammary gland

5 - 84

low - high

References: Heston WE, 1963;():247-68   ⋅   International Nomenclature Committee, Cancer Res 1952 Aug;12(8):602-13   ⋅   Murphy ED, 1966;():521-62   ⋅   Staats J, Companion to Mouse News Lett No. 21 1959;():   ⋅   Staats J, Companion to Mouse News Lett No. 33 1965;():

Mammary gland tumor Mammary gland methylcholanthrene (MCA)

30 - 80

References: Staats J, Companion to Mouse News Lett No. 33 1965;():

Myoepithelial cell myoepithelioma Salivary gland - Parotid

4

References: Murphy ED, 1966;():521-62

Myoepithelial cell myoepithelioma Myoepithelial cell

observed

References: Heston WE, 1963;():247-68   ⋅   Sundberg JP, Vet Pathol 1991 Jul;28(4):313-23

Reticular cell reticulum cell neoplasm Reticular cell

4

12

References: Staats J, Companion to Mouse News Lett No. 33 1965;():

Testis - Leydig cell (Interstitial cell) tumor Testis - Leydig cell (Interstitial cell) estrogen

observed

References: Festing MFW, Mouse Genome 1996;94(3):523-677   ⋅   Heston WE, 1963;():247-68   ⋅   Murphy ED, 1966;():521-62

(Unspecified organ) tumor (Unspecified organ) N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU)

0

References: Searle CE, Nature 1972 Dec 29;240(5383):559-60