Reference SummaryFrith CH, Lab Anim Sci 1982 Feb;32(1):60-3
Title |
Osteosarcomas in BALB/c female mice. |
Authors |
Frith CH; Johnson BP; Highman B |
Journal |
Lab Anim Sci |
Volume |
32 |
Issue |
1 |
Year |
1982 |
Pages |
60-3 |
Abstract |
Osteosarcomas were found in 16 of 24,192 (0.066%) BALB/c female mice, 14 were in 21,816 (0.064%) 2-acetylaminofluorene-treated mice, and two were in 2,376 (0.084%) untreated controls. The osteosarcomas were classified into osteoblastic, fibroblastic, and mixed types. Seven of the osteosarcomas metastasized to the lungs. The osteosarcomas in control and 2-acetylaminofluorene-treated mice showed little or no difference in the incidence, type, size, or site of origin, indicating that 2-acetylaminofluorene did not affect the development of osteosarcomas in BALB/c female mice.U |
Links |
J:41414 – MGI References 6952039 – National Library of Medicine/PubMed |
| Strain | Model Name | Treatment Agent(s) | Organ Affected | Frequency | Model Details |
|---|---|---|---|---|---|
| BALB/cStCrlfC3Hf/Nctr | Bone osteosarcoma | Bone |
0.1 |
||
| BALB/cStCrlfC3Hf/Nctr | Bone osteosarcoma |
|
Bone |
0.1 |
|
| BALB/c | Bone osteosarcoma - fibroblastic | Bone |
observed |