Strain SummaryBALB/c

Strain Name

 BALB/c

Strain Type(s)

 inbred

Strain Synonym(s)

 Bagg  •  Bagg albino  •  Bagg Albino  •  BALB  •  balb/c  •  B alb C  •  BALB/C  •  BALB/c (WT)  •  C  •  Cb  •  C strain  •  WT

Description

 Substrain not specified.

Strain Links

 • Festing's List of Inbred Strains

Models

114 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Adrenal gland - Cortex tumor Adrenal gland - Cortex

observed

References: Murphy ED, 1966;():521-62

Adrenal gland - Subcapsular cell hyperplasia Adrenal gland - Cortex

100

93

References: Kim JS, Exp Anim 1997 Oct;46(4):303-6

Blood vessel hemangioendothelioma Blood vessel 4-o-tolylazo-o-toluidine (2-amino-5-azotoluene)

observed

References: Deringer MK, J Natl Cancer Inst 1956;17(4):533-9

Blood vessel hemangioendothelioma Blood vessel o-aminoazotoluene

high

References: Festing MFW, Mouse Genome 1996;94(3):523-677   ⋅   Heston WE, 1963;():247-68

Blood vessel hemangiosarcoma Stomach - Glandular N-methyl-N-nitrosourea (MNU)

3.6 - 35

References: Yamachika T, Jpn J Cancer Res 1998 Apr;89(4):385-91

Blood vessel tumor - benign Spleen MoMuLV-TB - Moloney murine leukemia virus, TB strain   ⋅   R7 - MoMuSV 124 variant

70

References: Yuen PH, Am J Pathol 1998 Jun;152(6):1509-20

Bone osteosarcoma - fibroblastic Bone

observed

References: Frith CH, Lab Anim Sci 1982 Feb;32(1):60-3

Sites of Metastasis: Lung
Connective tissue - Fibroblast fibrosarcoma Connective tissue - Fibroblast 9,10-dimethyl-1,2-benzanthracene (DMBA)

17

7.7

References: Flaks A, Eur J Cancer 1968 Dec;4(6):579-85

Connective tissue - Fibroblast fibrosarcoma Connective tissue - Fibroblast MoMuLV-TB - Moloney murine leukemia virus, TB strain   ⋅   R7 - MoMuSV 124 variant

100

References: Yuen PH, Am J Pathol 1998 Jun;152(6):1509-20

Connective tissue - Fibroblast tumor Lung MoMuLV-TB - Moloney murine leukemia virus, TB strain   ⋅   R7 - MoMuSV 124 variant

81

References: Yuen PH, Am J Pathol 1998 Jun;152(6):1509-20

Connective tissue - Fibroblast tumor Liver MoMuLV-TB - Moloney murine leukemia virus, TB strain   ⋅   R7 - MoMuSV 124 variant

observed

References: Yuen PH, Am J Pathol 1998 Jun;152(6):1509-20

Connective tissue - Synovium synovioma Connective tissue - Synovium

2.0 - 8.0

References: Festing MFW, Mouse Genome 1996;94(3):523-677

Intestine - Large Intestine - Colon adenocarcinoma Intestine - Large Intestine - Colon dextran sulfate sodium (DSS)   ⋅   cigarette smoke

25

References: Liu ES, Carcinogenesis 2003 Aug;24(8):1407-13

Intestine - Large Intestine - Colon adenoma Intestine - Large Intestine - Colon dextran sulfate sodium (DSS)

0

References: Liu ES, Carcinogenesis 2003 Aug;24(8):1407-13

Intestine - Large Intestine - Colon carcinoma Intestine - Large Intestine - Colon

0

References: Liu ES, Carcinogenesis 2003 Aug;24(8):1407-13

Intestine - Large Intestine - Colon carcinoma Intestine - Large Intestine - Colon cigarette smoke

0

References: Liu ES, Carcinogenesis 2003 Aug;24(8):1407-13

Intestine - Large Intestine - Colon dysplasia Intestine - Large Intestine - Colon dextran sulfate sodium (DSS)

0 - 9.1

References: Liu ES, Carcinogenesis 2003 Aug;24(8):1407-13

Intestine - Large Intestine - Colon dysplasia Intestine - Large Intestine - Colon dextran sulfate sodium (DSS)   ⋅   cigarette smoke

42 - 80

References: Liu ES, Carcinogenesis 2003 Aug;24(8):1407-13

Intestine - Large Intestine - Colon polyp - adenomatous Intestine - Large Intestine - Colon dextran sulfate sodium (DSS)

9.1

References: Liu ES, Carcinogenesis 2003 Aug;24(8):1407-13

Intestine - Large Intestine - Colon polyp - adenomatous Intestine - Large Intestine - Colon dextran sulfate sodium (DSS)   ⋅   cigarette smoke

58 - 80

References: Liu ES, Carcinogenesis 2003 Aug;24(8):1407-13

Intestine - Large Intestine adenocarcinoma Intestine - Large Intestine

0

References: Berg DJ, J Clin Invest 1996 Aug 15;98(4):1010-20

Intestine metaplasia Intestine N-methyl-N-nitrosourea (MNU)

0

References: Yamachika T, Jpn J Cancer Res 1998 Apr;89(4):385-91

Kidney adenocarcinoma Kidney

40

References: Murphy ED, 1966;():521-62

Kidney tumor Kidney

25.0 - 48.0

References: Festing MFW, Mouse Genome 1996;94(3):523-677

Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell plasmacytoma Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell mineral oil

observed

References: Festing MFW, Mouse Genome 1996;94(3):523-677   ⋅   Staats J, Cancer Res 1985 Mar;45(3):945-77

Leukocyte - Lymphocyte - Pre-B-lymphocyte hyperplasia Leukocyte - Lymphocyte - Pre-B-lymphocyte

0

References: Flemming A, Nat Immunol 2003 Jan;4(1):38-43

Leukocyte - Lymphocyte - Pre-B-lymphocyte tumor Leukocyte - Lymphocyte - Pre-B-lymphocyte

0.05

References: Flemming A, Nat Immunol 2003 Jan;4(1):38-43

Leukocyte - Lymphocyte - T-lymphocyte lymphoma Leukocyte - Lymphocyte - T-lymphocyte MoMuLV-TB - Moloney murine leukemia virus, TB strain

observed

References: Yuen PH, Am J Pathol 1998 Jun;152(6):1509-20

Leukocyte - Lymphocyte leukemia - lymphocytic Leukocyte - Lymphocyte

0

References: Festing MFW, Mouse Genome 1996;94(3):523-677

Leukocyte - Lymphocyte lymphoma - small lymphocytic Leukocyte - Lymphocyte

5

References: Festing MFW, Mouse Genome 1996;94(3):523-677

Leukocyte leukemia Leukocyte

12 - 14

0 - 10

5

References: Festing MFW, Mouse Genome 1996;94(3):523-677   ⋅   Flaks A, Eur J Cancer 1968 Dec;4(6):579-85   ⋅   Staats J, Companion to Mouse News Lett No. 33 1965;():

Leukocyte leukemia Leukocyte 9,10-dimethyl-1,2-benzanthracene (DMBA)

52

35

References: Flaks A, Eur J Cancer 1968 Dec;4(6):579-85

Leukocyte leukemia Leukocyte dimethylbenzanthracene (DMBA)

observed

References: Festing MFW, Mouse Genome 1996;94(3):523-677

Leukocyte leukemia Leukocyte Friend leukemia virus (FLV)

observed

References: Festing MFW, Mouse Genome 1996;94(3):523-677

Leukocyte lymphoma Leukocyte A-MuLV - Abelson murine leukemia virus (A-MuLV-P160)

95 - 100

References: Risser R, Curr Top Microbiol Immunol 1985;122():162-8

Leukocyte lymphoma Leukocyte MoMuLV - Moloney murine leukemia virus (M-MuLV) (MMLV)

0 - 93

References: Risser R, Curr Top Microbiol Immunol 1985;122():162-8

Liver hepatoma Liver

0

0

References: Flaks A, Eur J Cancer 1968 Dec;4(6):579-85

Liver hepatoma Liver 9,10-dimethyl-1,2-benzanthracene (DMBA)

0

12

References: Flaks A, Eur J Cancer 1968 Dec;4(6):579-85

Liver hepatoma - malignant Liver 9,10-dimethyl-1,2-benzanthracene (DMBA)

0

0

References: Flaks A, Eur J Cancer 1968 Dec;4(6):579-85

Lung - Alveolus tumor Lung - Alveolus

high

References: Murphy ED, 1966;():521-62

Lung adenoma Lung

5.3 - 10

1.7

References: Flaks A, Eur J Cancer 1968 Dec;4(6):579-85   ⋅   Gordon T, Cancer Lett 2009 Mar 18;275(2):213-20

Lung adenoma Lung 9,10-dimethyl-1,2-benzanthracene (DMBA)

100

92

References: Flaks A, Eur J Cancer 1968 Dec;4(6):579-85

Lung adenoma Lung mainstream cigarette smoke (MCS)

21.05

References: Gordon T, Cancer Lett 2009 Mar 18;275(2):213-20

Lung carcinoma Lung 9,10-dimethyl-1,2-benzanthracene (DMBA)

8.7

27

References: Flaks A, Eur J Cancer 1968 Dec;4(6):579-85

Lung carcinoma Lung mainstream cigarette smoke (MCS)

0

References: Gordon T, Cancer Lett 2009 Mar 18;275(2):213-20

Lung carcinoma Lung

0

References: Gordon T, Cancer Lett 2009 Mar 18;275(2):213-20

Lung hyperplasia Lung

observed

References: Gordon T, Cancer Lett 2009 Mar 18;275(2):213-20

Lung hyperplasia Lung mainstream cigarette smoke (MCS)

observed

References: Gordon T, Cancer Lett 2009 Mar 18;275(2):213-20

Lung papilloma Lung

0

References: Gordon T, Cancer Lett 2009 Mar 18;275(2):213-20

Lung papilloma Lung mainstream cigarette smoke (MCS)

0

References: Gordon T, Cancer Lett 2009 Mar 18;275(2):213-20

Lung tumor Lung

observed - 35

29 - 45

observed - 37

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105   ⋅   Festing MFW, Mouse Genome 1996;94(3):523-677   ⋅   Gordon T, Cancer Lett 2009 Mar 18;275(2):213-20   ⋅   Heston WE, 1963;():247-68   ⋅   Lynch CJ, J Exp Med 1926;43():339-55   ⋅   Shimkin MB, Adv Cancer Res 1975;21():1-58   ⋅   Smith CS, Proc Soc Exp Biol Med 1971 Nov;138(2):542-4   ⋅   Staats J, Cancer Res 1985 Mar;45(3):945-77

Lung tumor Lung methylcholanthrene (MCA)

high

References: Festing MFW, Mouse Genome 1996;94(3):523-677

Lung tumor Lung hydrazine sulfate

high - 100

References: Shimkin MB, Adv Cancer Res 1975;21():1-58   ⋅   Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung urethane (ethyl carbamate)

53 - 85

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung urethane (ethyl carbamate)   ⋅   thymectomy

very high

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung urethane (ethyl carbamate)   ⋅   splenectomy

very high

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung urethane (ethyl carbamate)   ⋅   cortisone

very high

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung isoniazid

100

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung isonicotinic acid

19

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung iproniazid

35

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung phenylhydrazine

53

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung benzoylhydrazine

90

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung 2-methoxybenzoylhydrazine

95

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung 4-methoxybenzoylhydrazine

95

References: Shimkin MB, Adv Cancer Res 1975;21():1-58

Lung tumor Lung mainstream cigarette smoke (MCS)

observed - 21.05

References: Gordon T, Cancer Lett 2009 Mar 18;275(2):213-20

Mammary gland adenoacanthoma Mammary gland

2.9

References: Imai S, J Natl Cancer Inst 1983 Sep;71(3):517-21

Mammary gland adenocarcinoma Mammary gland

observed - 5

0

References: Festing MFW, Mouse Genome 1996;94(3):523-677   ⋅   Mikaelian I, Personal Communication 2003;():

Sites of Metastasis: Liver

2 pathology image(s)
Mammary gland carcinoma Mammary gland corn oil   ⋅   7,12-dimethylbenz[a]anthracene (DMBA)

77

References: Craig-Schmidt M, Nutr Cancer 1993;20(2):99-106

Mammary gland carcinoma Mammary gland menhaden oil   ⋅   corn oil   ⋅   7,12-dimethylbenz[a]anthracene (DMBA)

36

References: Craig-Schmidt M, Nutr Cancer 1993;20(2):99-106

Mammary gland carcinoma Mammary gland corn oil   ⋅   7,12-dimethylbenz[a]anthracene (DMBA)   ⋅   coconut oil

45

References: Craig-Schmidt M, Nutr Cancer 1993;20(2):99-106

Mammary gland carcinoma Mammary gland

10

References: Schlom J, J Natl Cancer Inst 1973;51():541-51

Mammary gland carcinoma Mammary gland 9,10-dimethyl-1,2-benzanthracene (DMBA)

0

References: Flaks A, Eur J Cancer 1968 Dec;4(6):579-85

Mammary gland normal tissue (control) Mammary gland

not applicable

References: Zhu M, Genome Biol 2011;12(8):R77

Mammary gland tumor Mammary gland

0 - 27

observed - 30

References: Festing MFW, Mouse Genome 1996;94(3):523-677   ⋅   Heston WE, 1963;():247-68   ⋅   International Nomenclature Committee, Cancer Res 1952 Aug;12(8):602-13   ⋅   Kapoun AM, Oncogene 1997 Jun 19;14(24):2985-9   ⋅   Lynch CJ, J Exp Med 1926;43():339-55   ⋅   Staats J, Cancer Res 1985 Mar;45(3):945-77   ⋅   Staats J, Companion to Mouse News Lett No. 21 1959;():   ⋅   Staats J, Companion to Mouse News Lett No. 33 1965;():   ⋅   Vaidya AB, J Virol 1983 Jun;46(3):818-28

Mammary gland tumor Mammary gland pituitary isograft

0

References: Medina D, J Natl Cancer Inst 1969;42():303-310

Mammary gland tumor Mammary gland NIV - nodule-inducing virus

0

References: Medina D, J Natl Cancer Inst 1969;42():303-310

Mammary gland tumor Mammary gland methylcholanthrene (MCA)

8

References: Staats J, Companion to Mouse News Lett No. 33 1965;():

Mammary gland tumor Mammary gland MMTV - mouse mammary tumor virus

8

high

References: Heston WE, 1963;():247-68   ⋅   International Nomenclature Committee, Cancer Res 1952 Aug;12(8):602-13   ⋅   Staats J, Companion to Mouse News Lett No. 33 1965;():

Muscle - Striated - Skeletal - Diaphragm tumor Muscle - Striated - Skeletal - Diaphragm MoMuLV-TB - Moloney murine leukemia virus, TB strain   ⋅   R7 - MoMuSV 124 variant

observed

References: Yuen PH, Am J Pathol 1998 Jun;152(6):1509-20

Muscle - Striated - Skeletal rhabdomyosarcoma Muscle - Striated - Skeletal 9,10-dimethyl-1,2-benzanthracene (DMBA)

3.8

References: Flaks A, Eur J Cancer 1968 Dec;4(6):579-85

Myoepithelial cell myoepithelioma Salivary gland - Parotid

observed - 4

References: Frith CH, Lab Anim Sci 1983 Jun;33(3):273-86   ⋅   Murphy ED, 1966;():521-62

Myoepithelial cell myoepithelioma Myoepithelial cell

observed

References: Heston WE, 1963;():247-68   ⋅   Sundberg JP, Vet Pathol 1991 Jul;28(4):313-23

Ovary carcinoma Ovary 9,10-dimethyl-1,2-benzanthracene (DMBA)

0

References: Flaks A, Eur J Cancer 1968 Dec;4(6):579-85

Renal pelvis carcinoma Renal pelvis N-butyl-N-(4-hydroxybutyl)nitrosamine (BBN)

12.5

References: Yamamoto S, Carcinogenesis 1998 May;19(5):855-60

Reticular cell reticulum cell neoplasm Reticular cell

23

3

References: Festing MFW, Mouse Genome 1996;94(3):523-677

Salivary gland carcinoma Salivary gland 9,10-dimethyl-1,2-benzanthracene (DMBA)

3.8

References: Flaks A, Eur J Cancer 1968 Dec;4(6):579-85

Skin carcinoma Skin 12-O-tetradecanoylphorbol-13-acetate (TPA)   ⋅   7,12-dimethylbenz[a]anthracene (DMBA)

observed

References: Woodworth CD, Carcinogenesis 2004 Sep;25(9):1771-8

Skin papilloma Skin 12-O-tetradecanoylphorbol-13-acetate (TPA)   ⋅   7,12-dimethylbenz[a]anthracene (DMBA)

observed

References: Woodworth CD, Carcinogenesis 2004 Sep;25(9):1771-8

Skin tumor Skin N-methyl-N-nitrosourea (MNU)

observed

References: Festing MFW, Mouse Genome 1996;94(3):523-677

Stomach - Glandular adenocarcinoma Stomach - Glandular N-methyl-N-nitrosourea (MNU)

0 - 77

References: Furihata C, Jpn J Cancer Res 1997 Apr;88(4):363-8   ⋅   Kobayashi K, Jpn J Cancer Res 1997 Dec;88(12):1143-8   ⋅   Yamachika T, Jpn J Cancer Res 1998 Apr;89(4):385-91

Sites of Metastasis: Lymph node
Stomach - Glandular adenocarcinoma Stomach - Glandular catechol

0

References: Kobayashi K, Jpn J Cancer Res 1997 Dec;88(12):1143-8

Stomach - Glandular adenocarcinoma Stomach - Glandular catechol   ⋅   N-methyl-N-nitrosourea (MNU)

0 - 70

References: Kobayashi K, Jpn J Cancer Res 1997 Dec;88(12):1143-8

Stomach - Glandular adenocarcinoma Stomach - Glandular

0

References: Kobayashi K, Jpn J Cancer Res 1997 Dec;88(12):1143-8

Stomach - Glandular adenoma Stomach - Glandular N-methyl-N-nitrosourea (MNU)

53 - 64

References: Yamachika T, Jpn J Cancer Res 1998 Apr;89(4):385-91

Stomach - Glandular hyperplasia - adenomatous Stomach - Glandular N-methyl-N-nitrosourea (MNU)

observed

References: Furihata C, Jpn J Cancer Res 1997 Apr;88(4):363-8

Stomach - Glandular papilloma Stomach - Glandular N-methyl-N-nitrosourea (MNU)

observed

References: Furihata C, Jpn J Cancer Res 1997 Apr;88(4):363-8

Stomach - Glandular squamous cell carcinoma Stomach - Glandular N-methyl-N-nitrosourea (MNU)

observed

References: Furihata C, Jpn J Cancer Res 1997 Apr;88(4):363-8

Stomach adenoma Stomach N-methyl-N-nitrosourea (MNU)

0

References: Kobayashi K, Jpn J Cancer Res 1997 Dec;88(12):1143-8

Stomach adenoma Stomach catechol

0 - 33

References: Kobayashi K, Jpn J Cancer Res 1997 Dec;88(12):1143-8

Stomach adenoma Stomach catechol   ⋅   N-methyl-N-nitrosourea (MNU)

10 - 37

References: Kobayashi K, Jpn J Cancer Res 1997 Dec;88(12):1143-8

Stomach adenoma Stomach

0

References: Kobayashi K, Jpn J Cancer Res 1997 Dec;88(12):1143-8

Testis - Leydig cell (Interstitial cell) hyperplasia Testis - Leydig cell (Interstitial cell)

observed

References: Murphy ED, 1966;():521-62

Testis - Leydig cell (Interstitial cell) tumor Testis - Leydig cell (Interstitial cell)

observed

References: Murphy ED, 1966;():521-62

Testis - Leydig cell (Interstitial cell) tumor Testis - Leydig cell (Interstitial cell) estrogen

observed

References: Murphy ED, 1966;():521-62

Testis - Leydig cell (Interstitial cell) tumor Testis - Leydig cell (Interstitial cell) diethylstilbestrol (DES)

high

References: Festing MFW, Mouse Genome 1996;94(3):523-677   ⋅   Heston WE, 1963;():247-68

Thymus thymoma Thymus A-MuLV - Abelson murine leukemia virus (A-MuLV-P160)

10

References: Risser R, Curr Top Microbiol Immunol 1985;122():162-8

Ureter carcinoma Ureter N-butyl-N-(4-hydroxybutyl)nitrosamine (BBN)

0

References: Yamamoto S, Carcinogenesis 1998 May;19(5):855-60

Urinary bladder carcinoma Urinary bladder N-butyl-N-(4-hydroxybutyl)nitrosamine (BBN)

100

References: Yamamoto S, Carcinogenesis 1998 May;19(5):855-60

Uterus adenocarcinoma Uterus

observed

References: Murphy ED, 1966;():521-62

Uterus tumor Uterus dimethylbenzanthracene (DMBA)

observed

References: Festing MFW, Mouse Genome 1996;94(3):523-677

(Unspecified organ) angioendothelioma CNS - Brain MoMuLV-TB - Moloney murine leukemia virus, TB strain   ⋅   R7 - MoMuSV 124 variant

60

References: Yuen PH, Am J Pathol 1998 Jun;152(6):1509-20

(Unspecified organ) angioma (Unspecified organ)

6

References: Festing MFW, Mouse Genome 1996;94(3):523-677

(Unspecified organ) reticuloendothelial neoplasm (Unspecified organ)

11.0 - 20.0

References: Festing MFW, Mouse Genome 1996;94(3):523-677

(Unspecified organ) squamous cell carcinoma (Unspecified organ) 9,10-dimethyl-1,2-benzanthracene (DMBA)

8.7

References: Flaks A, Eur J Cancer 1968 Dec;4(6):579-85