Strain SummaryICR
Strain Name |
ICR |
Strain Type(s) |
outbred |
Strain Synonym(s) |
wt ICR |
Strain Links |
• Festing's List of Inbred Strains |
| Frequency | ||||||||
|---|---|---|---|---|---|---|---|---|
| Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
| Bone osteosarcoma | Bone | plutonium-239 |
2.0 - 10 |
References: Ellender M, Int J Radiat Biol 2001 Jan;77(1):41-52 |
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| CNS - Brain - Astrocyte astrocytoma | CNS - Brain - Astrocyte |
0 |
References: Ding H, Cancer Res 2003 Mar 1;63(5):1106-13 |
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| Intestine - Large Intestine - Colon - Distal carcinoma | Intestine - Large Intestine - Colon - Distal | azoxymethane (AOM) |
observed |
References: Fukutake M, Carcinogenesis 1998 Nov;19(11):1939-42 |
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| Intestine - Large Intestine - Colon - Distal carcinoma | Intestine - Large Intestine - Colon - Distal | nimesulide (4-nitro-2-phenoxymethanesulfonanilide) ⋅ azoxymethane (AOM) |
observed |
References: Fukutake M, Carcinogenesis 1998 Nov;19(11):1939-42 |
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| Intestine - Large Intestine - Colon - Medial carcinoma | Intestine - Large Intestine - Colon - Medial | azoxymethane (AOM) |
observed |
References: Fukutake M, Carcinogenesis 1998 Nov;19(11):1939-42 |
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| Intestine - Large Intestine - Colon - Medial carcinoma | Intestine - Large Intestine - Colon - Medial | nimesulide (4-nitro-2-phenoxymethanesulfonanilide) ⋅ azoxymethane (AOM) |
observed |
References: Fukutake M, Carcinogenesis 1998 Nov;19(11):1939-42 |
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| Intestine - Large Intestine - Colon - Proximal carcinoma | Intestine - Large Intestine - Colon - Proximal | azoxymethane (AOM) |
0 |
References: Fukutake M, Carcinogenesis 1998 Nov;19(11):1939-42 |
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| Intestine - Large Intestine - Colon - Proximal carcinoma | Intestine - Large Intestine - Colon - Proximal | nimesulide (4-nitro-2-phenoxymethanesulfonanilide) ⋅ azoxymethane (AOM) |
0 |
References: Fukutake M, Carcinogenesis 1998 Nov;19(11):1939-42 |
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| Intestine - Large Intestine - Colon adenocarcinoma | Intestine - Large Intestine - Colon | azoxymethane (AOM) |
observed |
References: Takahashi M, Carcinogenesis 2000 Jun;21(6):1117-20 |
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| Intestine - Large Intestine - Rectum carcinoma | Intestine - Large Intestine - Rectum | azoxymethane (AOM) |
observed |
References: Fukutake M, Carcinogenesis 1998 Nov;19(11):1939-42 |
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| Intestine - Large Intestine - Rectum carcinoma | Intestine - Large Intestine - Rectum | nimesulide (4-nitro-2-phenoxymethanesulfonanilide) ⋅ azoxymethane (AOM) |
observed |
References: Fukutake M, Carcinogenesis 1998 Nov;19(11):1939-42 |
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| Intestine - Large Intestine carcinoma | Intestine - Large Intestine | azoxymethane (AOM) |
50 |
References: Fukutake M, Carcinogenesis 1998 Nov;19(11):1939-42 |
||||
| Intestine - Large Intestine carcinoma | Intestine - Large Intestine | nimesulide (4-nitro-2-phenoxymethanesulfonanilide) ⋅ azoxymethane (AOM) |
25 - 32 |
References: Fukutake M, Carcinogenesis 1998 Nov;19(11):1939-42 |
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| Intestine - Large Intestine tumor | Intestine - Large Intestine |
0 |
References: Fukutake M, Carcinogenesis 1998 Nov;19(11):1939-42 |
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| Intestine - Large Intestine tumor | Intestine - Large Intestine | nimesulide (4-nitro-2-phenoxymethanesulfonanilide) |
0 |
References: Fukutake M, Carcinogenesis 1998 Nov;19(11):1939-42 |
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| Liver tumor | Liver | azoxymethane (AOM) |
32 |
References: Fukutake M, Carcinogenesis 1998 Nov;19(11):1939-42 |
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| Liver tumor | Liver | nimesulide (4-nitro-2-phenoxymethanesulfonanilide) ⋅ azoxymethane (AOM) |
27 - 30 |
References: Fukutake M, Carcinogenesis 1998 Nov;19(11):1939-42 |
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| Lung adenoma | Lung | nimesulide (4-nitro-2-phenoxymethanesulfonanilide) |
5 |
References: Fukutake M, Carcinogenesis 1998 Nov;19(11):1939-42 |
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| Lung tumor | Lung | azoxymethane (AOM) |
29 |
References: Fukutake M, Carcinogenesis 1998 Nov;19(11):1939-42 |
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| Lung tumor | Lung | nimesulide (4-nitro-2-phenoxymethanesulfonanilide) ⋅ azoxymethane (AOM) |
35 - 42.5 |
References: Fukutake M, Carcinogenesis 1998 Nov;19(11):1939-42 |
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| Ovary cyst | Ovary | 17beta-estradiol (E2) ⋅ N-methyl-N-nitrosourea (MNU) |
33.0 - 53.0 |
References: Niwa K, Jpn J Cancer Res 1998 May;89(5):502-9 |
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| Ovary cyst | Ovary | N-methyl-N-nitrosourea (MNU) ⋅ tamoxifen (TAM) |
24.0 - 25.0 |
References: Niwa K, Jpn J Cancer Res 1998 May;89(5):502-9 |
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| Ovary cyst | Ovary | tamoxifen (TAM) |
62.0 - 69.0 |
References: Niwa K, Jpn J Cancer Res 1998 May;89(5):502-9 |
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| Ovary cyst | Ovary | N-methyl-N-nitrosourea (MNU) |
14.0 - 20.0 |
References: Niwa K, Jpn J Cancer Res 1998 May;89(5):502-9 |
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| Ovary tumor | Ovary | 17beta-estradiol (E2) ⋅ N-methyl-N-nitrosourea (MNU) |
0 |
References: Niwa K, Jpn J Cancer Res 1998 May;89(5):502-9 |
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| Ovary tumor | Ovary | N-methyl-N-nitrosourea (MNU) ⋅ tamoxifen (TAM) |
0 |
References: Niwa K, Jpn J Cancer Res 1998 May;89(5):502-9 |
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| Ovary tumor | Ovary | tamoxifen (TAM) |
0 |
References: Niwa K, Jpn J Cancer Res 1998 May;89(5):502-9 |
||||
| Ovary tumor | Ovary | N-methyl-N-nitrosourea (MNU) |
0 |
References: Niwa K, Jpn J Cancer Res 1998 May;89(5):502-9 |
||||
| Oviduct hyperplasia | Oviduct | 17beta-estradiol (E2) ⋅ N-methyl-N-nitrosourea (MNU) |
55.0 - 94.0 |
References: Niwa K, Jpn J Cancer Res 1998 May;89(5):502-9 |
||||
| Oviduct hyperplasia | Oviduct | N-methyl-N-nitrosourea (MNU) ⋅ tamoxifen (TAM) |
100 |
References: Niwa K, Jpn J Cancer Res 1998 May;89(5):502-9 |
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| Oviduct hyperplasia | Oviduct | tamoxifen (TAM) |
100 |
References: Niwa K, Jpn J Cancer Res 1998 May;89(5):502-9 |
||||
| Oviduct hyperplasia | Oviduct | N-methyl-N-nitrosourea (MNU) |
11 |
References: Niwa K, Jpn J Cancer Res 1998 May;89(5):502-9 |
||||
| Oviduct tumor | Oviduct | 17beta-estradiol (E2) ⋅ N-methyl-N-nitrosourea (MNU) |
0 |
References: Niwa K, Jpn J Cancer Res 1998 May;89(5):502-9 |
||||
| Oviduct tumor | Oviduct | N-methyl-N-nitrosourea (MNU) ⋅ tamoxifen (TAM) |
0 |
References: Niwa K, Jpn J Cancer Res 1998 May;89(5):502-9 |
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| Oviduct tumor | Oviduct | tamoxifen (TAM) |
0 |
References: Niwa K, Jpn J Cancer Res 1998 May;89(5):502-9 |
||||
| Oviduct tumor | Oviduct | N-methyl-N-nitrosourea (MNU) |
0 |
References: Niwa K, Jpn J Cancer Res 1998 May;89(5):502-9 |
||||
| Uterus - Endometrium adenocarcinoma | Uterus - Endometrium | 17beta-estradiol (E2) ⋅ N-methyl-N-nitrosourea (MNU) |
38 - 67 |
References: Niwa K, Jpn J Cancer Res 1998 May;89(5):502-9 |
||||
| Uterus - Endometrium adenocarcinoma | Uterus - Endometrium | N-methyl-N-nitrosourea (MNU) ⋅ tamoxifen (TAM) |
17 |
References: Niwa K, Jpn J Cancer Res 1998 May;89(5):502-9 |
||||
| Uterus - Endometrium adenocarcinoma | Uterus - Endometrium | tamoxifen (TAM) |
0 |
References: Niwa K, Jpn J Cancer Res 1998 May;89(5):502-9 |
||||
| Uterus - Endometrium adenocarcinoma | Uterus - Endometrium | N-methyl-N-nitrosourea (MNU) |
12 |
References: Niwa K, Jpn J Cancer Res 1998 May;89(5):502-9 |
||||
| Uterus - Endometrium hyperplasia - atypical | Uterus - Endometrium | 17beta-estradiol (E2) ⋅ N-methyl-N-nitrosourea (MNU) |
67 - 83 |
References: Niwa K, Jpn J Cancer Res 1998 May;89(5):502-9 |
||||
| Uterus - Endometrium hyperplasia - atypical | Uterus - Endometrium | N-methyl-N-nitrosourea (MNU) ⋅ tamoxifen (TAM) |
63 |
References: Niwa K, Jpn J Cancer Res 1998 May;89(5):502-9 |
||||
| Uterus - Endometrium hyperplasia - atypical | Uterus - Endometrium | tamoxifen (TAM) |
5 |
References: Niwa K, Jpn J Cancer Res 1998 May;89(5):502-9 |
||||
| Uterus - Endometrium hyperplasia - atypical | Uterus - Endometrium | N-methyl-N-nitrosourea (MNU) |
38 |
References: Niwa K, Jpn J Cancer Res 1998 May;89(5):502-9 |
||||
| Uterus - Endometrium hyperplasia - complex | Uterus - Endometrium | 17beta-estradiol (E2) ⋅ N-methyl-N-nitrosourea (MNU) |
96 - 97 |
References: Niwa K, Jpn J Cancer Res 1998 May;89(5):502-9 |
||||
| Uterus - Endometrium hyperplasia - complex | Uterus - Endometrium | N-methyl-N-nitrosourea (MNU) ⋅ tamoxifen (for inducing expression from mutant alleles) |
92 |
References: Niwa K, Jpn J Cancer Res 1998 May;89(5):502-9 |
||||
| Uterus - Endometrium hyperplasia - complex | Uterus - Endometrium | tamoxifen (TAM) |
57 |
References: Niwa K, Jpn J Cancer Res 1998 May;89(5):502-9 |
||||
| Uterus - Endometrium hyperplasia - complex | Uterus - Endometrium | N-methyl-N-nitrosourea (MNU) |
76 |
References: Niwa K, Jpn J Cancer Res 1998 May;89(5):502-9 |
||||
| Uterus - Endometrium hyperplasia - simple | Uterus - Endometrium | 17beta-estradiol (E2) ⋅ N-methyl-N-nitrosourea (MNU) |
92 - 97 |
References: Niwa K, Jpn J Cancer Res 1998 May;89(5):502-9 |
||||
| Uterus - Endometrium hyperplasia - simple | Uterus - Endometrium | N-methyl-N-nitrosourea (MNU) ⋅ tamoxifen (TAM) |
96 |
References: Niwa K, Jpn J Cancer Res 1998 May;89(5):502-9 |
||||
| Uterus - Endometrium hyperplasia - simple | Uterus - Endometrium | tamoxifen (TAM) |
96 |
References: Niwa K, Jpn J Cancer Res 1998 May;89(5):502-9 |
||||
| Uterus - Endometrium hyperplasia - simple | Uterus - Endometrium | N-methyl-N-nitrosourea (MNU) |
18 |
References: Niwa K, Jpn J Cancer Res 1998 May;89(5):502-9 |
||||
| Vagina tumor | Vagina | 17beta-estradiol (E2) ⋅ N-methyl-N-nitrosourea (MNU) |
0 |
References: Niwa K, Jpn J Cancer Res 1998 May;89(5):502-9 |
||||
| Vagina tumor | Vagina | N-methyl-N-nitrosourea (MNU) ⋅ tamoxifen (TAM) |
0 |
References: Niwa K, Jpn J Cancer Res 1998 May;89(5):502-9 |
||||
| Vagina tumor | Vagina | tamoxifen (TAM) |
0 |
References: Niwa K, Jpn J Cancer Res 1998 May;89(5):502-9 |
||||
| Vagina tumor | Vagina | N-methyl-N-nitrosourea (MNU) |
0 |
References: Niwa K, Jpn J Cancer Res 1998 May;89(5):502-9 |
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