Strain SummaryB6129P2F1-Apctm1Rak/+
Strain Name |
B6129P2F1-Apctm1Rak/+ |
Strain Type(s) |
hybrid • targeted mutation (knockout) |
Strain Synonym(s) |
Apc1638 • B6,129-Apctm1Rak/+ • Apc1638 |
Description |
Heterozygous mice carrying the Apctm1Rak mutation. The genetic background is 50% C57BL/6J, 50% 129P2/OlaHsd. |
Strain Genetics |
Apctm1Rak / Apc+ |
Frequency | ||||||||
---|---|---|---|---|---|---|---|---|
Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Gastrointestinal tract tumor | Gastrointestinal tract |
62.5 |
References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54 |
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Intestine - Large Intestine - Cecum tumor | Intestine - Large Intestine - Cecum |
0 |
References: Fodde R, Proc Natl Acad Sci U S A 1994 Sep 13;91(19):8969-73 |
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Intestine - Large Intestine - Colon - Distal adenocarcinoma | Intestine - Large Intestine - Colon - Distal |
0 |
References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54 |
|||||
Intestine - Large Intestine - Colon - Distal adenoma | Intestine - Large Intestine - Colon - Distal |
4.2 - 9.1 |
References: Fodde R, Proc Natl Acad Sci U S A 1994 Sep 13;91(19):8969-73 ⋅ Yang K, J Exp Zool 1997 Feb 15;277(3):245-54 |
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Intestine - Large Intestine - Colon - Distal polyp | Intestine - Large Intestine - Colon - Distal |
55 |
References: Fodde R, Proc Natl Acad Sci U S A 1994 Sep 13;91(19):8969-73 |
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Intestine - Large Intestine - Colon - Medial adenocarcinoma | Intestine - Large Intestine - Colon - Medial |
0 |
References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54 |
|||||
Intestine - Large Intestine - Colon - Medial adenoma | Intestine - Large Intestine - Colon - Medial |
0 |
References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54 |
|||||
Intestine - Large Intestine - Colon - Medial polyp | Intestine - Large Intestine - Colon - Medial |
9.1 |
References: Fodde R, Proc Natl Acad Sci U S A 1994 Sep 13;91(19):8969-73 |
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Intestine - Large Intestine - Colon - Proximal adenocarcinoma | Intestine - Large Intestine - Colon - Proximal |
0 |
References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54 |
|||||
Intestine - Large Intestine - Colon - Proximal adenoma | Intestine - Large Intestine - Colon - Proximal |
4.2 - 9.1 |
References: Fodde R, Proc Natl Acad Sci U S A 1994 Sep 13;91(19):8969-73 ⋅ Yang K, J Exp Zool 1997 Feb 15;277(3):245-54 |
|||||
Intestine - Large Intestine - Colon - Proximal polyp | Intestine - Large Intestine - Colon - Proximal |
27 |
References: Fodde R, Proc Natl Acad Sci U S A 1994 Sep 13;91(19):8969-73 |
|||||
Intestine - Large Intestine - Colon dysplasia | Intestine - Large Intestine - Colon |
17 |
References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54 |
|||||
Intestine - Large Intestine - Colon polyp | Intestine - Large Intestine - Colon |
observed |
References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54 |
|||||
Intestine - Large Intestine - Colon tumor | Intestine - Large Intestine - Colon |
8.3 |
References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54 |
|||||
Intestine - Small Intestine - Duodenum adenocarcinoma | Intestine - Small Intestine - Duodenum |
observed |
References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54 |
|||||
Intestine - Small Intestine - Duodenum adenoma | Intestine - Small Intestine - Duodenum |
observed - 36 |
References: Fodde R, Proc Natl Acad Sci U S A 1994 Sep 13;91(19):8969-73 ⋅ Yang K, J Exp Zool 1997 Feb 15;277(3):245-54 |
|||||
Intestine - Small Intestine - Duodenum carcinoma | Intestine - Small Intestine - Duodenum |
27 |
References: Fodde R, Proc Natl Acad Sci U S A 1994 Sep 13;91(19):8969-73 |
|||||
Intestine - Small Intestine - Duodenum dysplasia | Intestine - Small Intestine - Duodenum |
17 |
References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54 |
|||||
Intestine - Small Intestine - Duodenum tumor | Intestine - Small Intestine - Duodenum |
42 |
References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54 |
|||||
Intestine - Small Intestine - Ileum adenocarcinoma | Intestine - Small Intestine - Ileum |
12.5 |
References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54 |
|||||
Intestine - Small Intestine - Ileum adenoma | Intestine - Small Intestine - Ileum |
4.2 - 9.1 |
References: Fodde R, Proc Natl Acad Sci U S A 1994 Sep 13;91(19):8969-73 ⋅ Yang K, J Exp Zool 1997 Feb 15;277(3):245-54 |
|||||
Intestine - Small Intestine - Ileum carcinoma | Intestine - Small Intestine - Ileum |
18 |
References: Fodde R, Proc Natl Acad Sci U S A 1994 Sep 13;91(19):8969-73 Sites of Metastasis: Liver |
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Intestine - Small Intestine - Ileum tumor | Intestine - Small Intestine - Ileum |
17 |
References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54 |
|||||
Intestine - Small Intestine - Jejunum adenocarcinoma | Intestine - Small Intestine - Jejunum |
observed |
References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54 |
|||||
Intestine - Small Intestine - Jejunum adenoma | Intestine - Small Intestine - Jejunum |
observed - 18 |
References: Fodde R, Proc Natl Acad Sci U S A 1994 Sep 13;91(19):8969-73 ⋅ Yang K, J Exp Zool 1997 Feb 15;277(3):245-54 |
|||||
Intestine - Small Intestine - Jejunum carcinoma | Intestine - Small Intestine - Jejunum |
27 |
References: Fodde R, Proc Natl Acad Sci U S A 1994 Sep 13;91(19):8969-73 |
|||||
Intestine - Small Intestine - Jejunum tumor | Intestine - Small Intestine - Jejunum |
37.5 |
References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54 |
|||||
Intestine dysplasia | Intestine |
50 |
References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54 |
|||||
Stomach - Glandular adenoma | Stomach - Glandular |
13 |
References: Fodde R, Proc Natl Acad Sci U S A 1994 Sep 13;91(19):8969-73 |
|||||
Stomach - Glandular carcinoma | Stomach - Glandular |
13 |
References: Fodde R, Proc Natl Acad Sci U S A 1994 Sep 13;91(19):8969-73 |
|||||
Stomach adenocarcinoma | Stomach |
observed |
References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54 |
|||||
Stomach adenoma | Stomach |
observed |
References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54 |
|||||
Stomach dysplasia | Stomach |
17 |
References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54 |
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Stomach tumor | Stomach |
25 |
References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54 |