Strain SummaryB6;129S1-Pten^tm1Rps/+

Strain Name	B6;129S1-Pten^tm1Rps/+
Strain Type(s)	targeted mutation (knockout)
Strain Synonym(s)	B6/129 Pten+/- • Pten+/-
Description	Mice heterozygous for a targeted mutation of Pten. The genetic background was a mix of C57BL/6J and 129S1.
Strain Genetics	List all models in MMHCdb carrying the Pten^tm1Rps allele Pten^tm1Rps / Pten⁺

Models
17 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
CNS - Brain tumor	CNS - Brain				0		References: Podsypanina K, Proc Natl Acad Sci U S A 1999 Feb 16;96(4):1563-8
Intestine - Large Intestine - Colon adenoma	Intestine - Large Intestine - Colon				1.2		References: Podsypanina K, Proc Natl Acad Sci U S A 1999 Feb 16;96(4):1563-8
Intestine polyp	Intestine				100		References: Podsypanina K, Proc Natl Acad Sci U S A 1999 Feb 16;96(4):1563-8
Leukocyte - Lymphoblast lymphoma	Leukocyte - Lymphoblast				2.7		References: Podsypanina K, Proc Natl Acad Sci U S A 1999 Feb 16;96(4):1563-8
Leukocyte - Lymphoblast lymphoma	Kidney				observed		References: Podsypanina K, Proc Natl Acad Sci U S A 1999 Feb 16;96(4):1563-8 1 pathology image(s)
Leukocyte leukemia	Leukocyte				0.4		References: Podsypanina K, Proc Natl Acad Sci U S A 1999 Feb 16;96(4):1563-8
Liver adenoma	Liver				0.4		References: Podsypanina K, Proc Natl Acad Sci U S A 1999 Feb 16;96(4):1563-8
Lymph node hyperplasia	Lymph node				73		References: Podsypanina K, Proc Natl Acad Sci U S A 1999 Feb 16;96(4):1563-8
Mammary gland neoplasia	Mammary gland				0		References: Podsypanina K, Proc Natl Acad Sci U S A 1999 Feb 16;96(4):1563-8
Ovary - Germ cell teratoma	Uterus				0.4		References: Podsypanina K, Proc Natl Acad Sci U S A 1999 Feb 16;96(4):1563-8
Prostate gland hyperplasia	Prostate gland			38			References: Podsypanina K, Proc Natl Acad Sci U S A 1999 Feb 16;96(4):1563-8
Prostate gland prostatic intraepithelial neoplasia (PIN)	Prostate gland			38			References: Podsypanina K, Proc Natl Acad Sci U S A 1999 Feb 16;96(4):1563-8 1 pathology image(s)
Skin neoplasia	Skin				0		References: Podsypanina K, Proc Natl Acad Sci U S A 1999 Feb 16;96(4):1563-8
Testis tumor	Testis			0			References: Podsypanina K, Proc Natl Acad Sci U S A 1999 Feb 16;96(4):1563-8
Thyroid gland - Follicular cell neoplasia	Thyroid gland - Follicular cell				15		References: Podsypanina K, Proc Natl Acad Sci U S A 1999 Feb 16;96(4):1563-8
Thyroid gland carcinoma	Thyroid gland				0.4		References: Podsypanina K, Proc Natl Acad Sci U S A 1999 Feb 16;96(4):1563-8 2 pathology image(s)
Uterus - Endometrium hyperplasia	Uterus - Endometrium		100				References: Podsypanina K, Proc Natl Acad Sci U S A 1999 Feb 16;96(4):1563-8 2 pathology image(s)