Strain SummaryC57BL/6J +/+ : 129S1/Sv p⁺ Tyr⁺ Kitl⁺ Pten^tm1Rps/+

Strain Name	C57BL/6J +/+ : 129S1/Sv p⁺ Tyr⁺ Kitl⁺ Pten^tm1Rps/+
Strain Type(s)	chimeric • targeted mutation (knockout)
Strain Synonym(s)	129SvJ/C57B6 chimera • Pten+/- chimera
Description	Chimeric mice generated by injection of gene-targeted W9.5 ES cells into wild-type C57BL/6J blastocysts. The ES cells were heterozygous for a targeted mutation of the Pten gene, Pten^tm1Rps.
Strain Genetics	List all models in MMHCdb carrying the Pten^tm1Rps allele Pten^tm1Rps / Pten⁺
	Pten⁺ / Pten⁺

Models
3 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Intestine - Large Intestine polyp	Intestine - Large Intestine			89			References: Podsypanina K, Proc Natl Acad Sci U S A 1999 Feb 16;96(4):1563-8 3 pathology image(s)
Intestine - Small Intestine polyp	Intestine - Small Intestine			89			References: Podsypanina K, Proc Natl Acad Sci U S A 1999 Feb 16;96(4):1563-8 2 pathology image(s)
Testis - Germ cell teratoma	Testis - Germ cell			11			References: Podsypanina K, Proc Natl Acad Sci U S A 1999 Feb 16;96(4):1563-8

Models