Strain SummaryC57BL/6N
Strain Name |
C57BL/6N |
Strain Type(s) |
inbred |
Strain Synonym(s) |
C57BL/6 • C57BL6 |
Strain Links |
• Festing's List of Inbred Strains |
Frequency | ||||||||
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Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Blood vessel hemangioma | Liver |
1.4 |
References: Dasenbrock C, Exp Toxicol Pathol 2005 Apr;56(6):351-60 |
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Blood vessel hemangioma | Liver | X-radiation |
0.4 |
References: Dasenbrock C, Exp Toxicol Pathol 2005 Apr;56(6):351-60 |
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Blood vessel hemangiosarcoma | Liver |
1.4 |
References: Dasenbrock C, Exp Toxicol Pathol 2005 Apr;56(6):351-60 |
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Blood vessel hemangiosarcoma | Liver | X-radiation |
0.4 |
References: Dasenbrock C, Exp Toxicol Pathol 2005 Apr;56(6):351-60 |
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Blood vessel hemangiosarcoma | Spleen | N-methyl-N-nitrosourea (MNU) |
13.04 |
References: Yamamoto M, Cancer Lett 2002 May 28;179(2):121-32 |
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Blood vessel hemangiosarcoma | Liver | N-methyl-N-nitrosourea (MNU) |
8.7 |
References: Yamamoto M, Cancer Lett 2002 May 28;179(2):121-32 |
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Blood vessel hemangiosarcoma | Intestine | N-methyl-N-nitrosourea (MNU) |
34.78 |
References: Yamamoto M, Cancer Lett 2002 May 28;179(2):121-32 |
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Blood vessel tumor | Liver |
2.7 |
References: Dasenbrock C, Exp Toxicol Pathol 2005 Apr;56(6):351-60 |
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Blood vessel tumor | Liver | X-radiation |
0.9 |
References: Dasenbrock C, Exp Toxicol Pathol 2005 Apr;56(6):351-60 |
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Intestine adenocarcinoma | Intestine | N-methyl-N-nitrosourea (MNU) |
17.39 |
References: Yamamoto M, Cancer Lett 2002 May 28;179(2):121-32 |
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Intestine metaplasia | Intestine | N-methyl-N-nitrosourea (MNU) |
0 |
References: Yamamoto M, Cancer Lett 2002 May 28;179(2):121-32 |
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Intestine metaplasia | Intestine |
0 |
References: Yamamoto M, Cancer Lett 2002 May 28;179(2):121-32 |
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Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma | Leukocyte - Monocyte - Macrophage - Histiocyte |
11.4 |
References: Dasenbrock C, Exp Toxicol Pathol 2005 Apr;56(6):351-60 |
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Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma | Leukocyte - Monocyte - Macrophage - Histiocyte | X-radiation |
8.3 |
References: Dasenbrock C, Exp Toxicol Pathol 2005 Apr;56(6):351-60 |
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Leukocyte - Myelocyte (Granulocyte) leukemia - myelocytic | Leukocyte - Myelocyte (Granulocyte) |
1.4 |
References: Dasenbrock C, Exp Toxicol Pathol 2005 Apr;56(6):351-60 |
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Leukocyte - Myelocyte (Granulocyte) leukemia - myelocytic | Leukocyte - Myelocyte (Granulocyte) | X-radiation |
1.3 |
References: Dasenbrock C, Exp Toxicol Pathol 2005 Apr;56(6):351-60 |
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Leukocyte lymphoma | Leukocyte |
50.7 |
observed |
References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105 ⋅ Dasenbrock C, Exp Toxicol Pathol 2005 Apr;56(6):351-60 |
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Leukocyte lymphoma | Leukocyte | X-radiation |
59.1 |
References: Dasenbrock C, Exp Toxicol Pathol 2005 Apr;56(6):351-60 |
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Leukocyte lymphoma | Spleen | N-methyl-N-nitrosourea (MNU) |
0 |
References: Yamamoto M, Cancer Lett 2002 May 28;179(2):121-32 |
||||
Leukocyte lymphoma | Thymus | N-methyl-N-nitrosourea (MNU) |
0 |
References: Yamamoto M, Cancer Lett 2002 May 28;179(2):121-32 |
||||
Liver hepatocellular adenoma | Liver |
2.7 |
References: Dasenbrock C, Exp Toxicol Pathol 2005 Apr;56(6):351-60 |
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Liver hepatocellular adenoma | Liver | X-radiation |
3.9 |
References: Dasenbrock C, Exp Toxicol Pathol 2005 Apr;56(6):351-60 |
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Liver hepatocellular carcinoma | Liver |
0.5 |
References: Dasenbrock C, Exp Toxicol Pathol 2005 Apr;56(6):351-60 |
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Liver hepatocellular carcinoma | Liver | X-radiation |
3.9 |
References: Dasenbrock C, Exp Toxicol Pathol 2005 Apr;56(6):351-60 |
||||
Liver hepatocellular carcinoma | Liver | N-methyl-N-nitrosourea (MNU) |
0 |
References: Yamamoto M, Cancer Lett 2002 May 28;179(2):121-32 |
||||
Liver hepatocellular tumor | Liver |
3.2 |
References: Dasenbrock C, Exp Toxicol Pathol 2005 Apr;56(6):351-60 |
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Liver hepatocellular tumor | Liver | X-radiation |
7.8 |
References: Dasenbrock C, Exp Toxicol Pathol 2005 Apr;56(6):351-60 |
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Lung adenocarcinoma | Lung | N-methyl-N-nitrosourea (MNU) |
4.35 |
References: Yamamoto M, Cancer Lett 2002 May 28;179(2):121-32 |
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Lung adenoma | Lung |
2.3 |
References: Dasenbrock C, Exp Toxicol Pathol 2005 Apr;56(6):351-60 |
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Lung adenoma | Lung | X-radiation |
7.0 |
References: Dasenbrock C, Exp Toxicol Pathol 2005 Apr;56(6):351-60 |
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Lung carcinoma | Lung |
0.9 |
References: Dasenbrock C, Exp Toxicol Pathol 2005 Apr;56(6):351-60 |
|||||
Lung carcinoma | Lung | X-radiation |
3.9 |
References: Dasenbrock C, Exp Toxicol Pathol 2005 Apr;56(6):351-60 |
||||
Lung papilloma | Lung |
0 |
References: Dasenbrock C, Exp Toxicol Pathol 2005 Apr;56(6):351-60 |
|||||
Lung papilloma | Lung | X-radiation |
0.4 |
References: Dasenbrock C, Exp Toxicol Pathol 2005 Apr;56(6):351-60 |
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Lung tumor | Lung | urethane (ethyl carbamate) |
16 |
References: Chen B, Proc Natl Acad Sci U S A 1994 Feb 15;91(4):1589-93 |
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Lung tumor | Lung |
3.2 |
References: Dasenbrock C, Exp Toxicol Pathol 2005 Apr;56(6):351-60 |
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Lung tumor | Lung | X-radiation |
10.9 |
References: Dasenbrock C, Exp Toxicol Pathol 2005 Apr;56(6):351-60 |
||||
Stomach - Glandular - Pylorus hyperplasia | Stomach - Glandular - Pylorus | N-methyl-N-nitrosourea (MNU) |
observed |
References: Yamamoto M, Cancer Lett 2002 May 28;179(2):121-32 |
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Stomach - Glandular - Pylorus hyperplasia | Stomach - Glandular - Pylorus |
0 |
References: Yamamoto M, Cancer Lett 2002 May 28;179(2):121-32 |
|||||
Stomach - Glandular - Pylorus lesion | Stomach - Glandular - Pylorus | N-methyl-N-nitrosourea (MNU) |
100 |
References: Yamamoto M, Cancer Lett 2002 May 28;179(2):121-32 |
||||
Stomach - Glandular - Pylorus lesion | Stomach - Glandular - Pylorus |
100 |
References: Yamamoto M, Cancer Lett 2002 May 28;179(2):121-32 |
|||||
Stomach - Glandular - Pylorus preneoplastic lesion | Stomach - Glandular - Pylorus | N-methyl-N-nitrosourea (MNU) |
observed |
References: Yamamoto M, Cancer Lett 2002 May 28;179(2):121-32 |
||||
Stomach - Glandular - Pylorus preneoplastic lesion | Stomach - Glandular - Pylorus |
0 |
References: Yamamoto M, Cancer Lett 2002 May 28;179(2):121-32 |
|||||
Stomach - Glandular - Pylorus tumor | Stomach - Glandular - Pylorus | N-methyl-N-nitrosourea (MNU) |
0 |
References: Yamamoto M, Cancer Lett 2002 May 28;179(2):121-32 |
||||
Stomach - Glandular - Pylorus tumor | Stomach - Glandular - Pylorus |
0 |
References: Yamamoto M, Cancer Lett 2002 May 28;179(2):121-32 |
|||||
Stomach - Glandular adenocarcinoma | Stomach - Glandular | N-methyl-N-nitrosourea (MNU) |
31.82 |
References: Yamamoto M, Cancer Lett 2002 May 28;179(2):121-32 |
||||
Stomach - Glandular adenocarcinoma | Stomach - Glandular |
0 |
References: Yamamoto M, Cancer Lett 2002 May 28;179(2):121-32 |
|||||
Stomach - Glandular adenocarcinoma - poorly differentiated | Stomach - Glandular | N-methyl-N-nitrosourea (MNU) |
0 |
References: Yamamoto M, Cancer Lett 2002 May 28;179(2):121-32 |
||||
Stomach - Glandular adenocarcinoma - signet ring cell | Stomach - Glandular | N-methyl-N-nitrosourea (MNU) |
0 |
References: Yamamoto M, Cancer Lett 2002 May 28;179(2):121-32 |
||||
Stomach - Glandular adenocarcinoma - well-differentiated | Stomach - Glandular | N-methyl-N-nitrosourea (MNU) |
observed |
References: Yamamoto M, Cancer Lett 2002 May 28;179(2):121-32 |
||||
Stomach - Glandular adenoma | Stomach - Glandular | N-methyl-N-nitrosourea (MNU) |
54.55 |
References: Yamamoto M, Cancer Lett 2002 May 28;179(2):121-32 |
||||
Stomach - Glandular adenoma | Stomach - Glandular |
0 |
References: Yamamoto M, Cancer Lett 2002 May 28;179(2):121-32 |
|||||
Stomach - Glandular tumor | Stomach - Glandular | N-methyl-N-nitrosourea (MNU) |
observed |
References: Yamamoto M, Cancer Lett 2002 May 28;179(2):121-32 |
||||
Stomach - Glandular tumor | Stomach - Glandular |
0 |
References: Yamamoto M, Cancer Lett 2002 May 28;179(2):121-32 |
|||||
Stomach adenocarcinoma | Stomach | N-methyl-N-nitrosourea (MNU) |
33.33 |
References: Yamamoto M, Cancer Lett 2002 May 28;179(2):121-32 |
||||
Stomach adenocarcinoma - well-differentiated | Stomach | N-methyl-N-nitrosourea (MNU) |
observed |
References: Yamamoto M, Cancer Lett 2002 May 28;179(2):121-32 |
||||
Stomach tumor | Stomach | N-methyl-N-nitrosourea (MNU) |
observed |
References: Yamamoto M, Cancer Lett 2002 May 28;179(2):121-32 |
||||
(Unspecified organ) tumor | (Unspecified organ) |
63.5 |
References: Dasenbrock C, Exp Toxicol Pathol 2005 Apr;56(6):351-60 |
|||||
(Unspecified organ) tumor | (Unspecified organ) | X-radiation |
68.7 |
References: Dasenbrock C, Exp Toxicol Pathol 2005 Apr;56(6):351-60 |