Strain SummarySTOCK Cdkn2btm1Bpd Tg(MSV-Rgl2)#Pel
Strain Name |
STOCK Cdkn2btm1Bpd Tg(MSV-Rgl2)#Pel |
Strain Type(s) |
targeted mutation (knockout) • transgenic |
Strain Synonym(s) |
MSV-RGR/KO-p15INK4b |
Description |
Mice had a mixed background with contributions from 129/Sv, C57BL/6, and FVB/N. Mice were homozygous for the Cdkn2btm1Bpd mutation and carried the Tg(MSV-Rgl2)#Pel transgene (not specified if line 21 or line 43). |
Strain Genetics |
Tg(MSV-Rgl2)#Pel |
Cdkn2btm1Bbd / Cdkn2btm1Bbd |
Frequency | ||||||||
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Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Connective tissue - Fibroblast fibrosarcoma | Limb - Hindlimb |
100 |
References: Jimenez M, Cancer Res 2004 Sep 1;64(17):6041-9 |
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Connective tissue - Fibroblast fibrosarcoma | Limb - Forelimb |
100 |
References: Jimenez M, Cancer Res 2004 Sep 1;64(17):6041-9 |
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Connective tissue - Fibroblast fibrosarcoma | Ear |
100 |
References: Jimenez M, Cancer Res 2004 Sep 1;64(17):6041-9 |
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Connective tissue - Fibroblast fibrosarcoma | Tail |
100 |
References: Jimenez M, Cancer Res 2004 Sep 1;64(17):6041-9 |
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Leukocyte lymphoma | Spleen |
50 |
References: Jimenez M, Cancer Res 2004 Sep 1;64(17):6041-9 |
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Lymphoid tissue hyperplasia | Spleen |
100 |
References: Jimenez M, Cancer Res 2004 Sep 1;64(17):6041-9 |