Strain SummaryBALB/cJ-Mapk8^tm1Flv Trp53^tm1Tyj

Strain Name	BALB/cJ-Mapk8^tm1Flv Trp53^tm1Tyj
Strain Type(s)	targeted mutation (knockout)
Strain Synonym(s)	Jnk1^-/- Trp53^-/- • Jnk1^-/- Trp53^-/- BALB/c
Description	Double homozygous mice. This cohort was generated by crossing congenic BALB/cJ mice carrying each of the mutations. Genetic background also contained some 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺ and some 129S2/SvPas.
Strain Genetics	List all models in MMHCdb carrying the Mapk8^tm1Flv allele Mapk8^tm1Flv / Mapk8^tm1Flv
	List all models in MMHCdb carrying the Trp53^tm1Tyj allele Trp53^tm1Tyj / Trp53^tm1Tyj

Models
6 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Blood vessel hemangiosarcoma	Blood vessel		very low	low			References: Cellurale C, PLoS One 2010;5(8):
Leukocyte lymphoma	Leukocyte		very high	very high			References: Cellurale C, PLoS One 2010;5(8):
Mammary gland carcinoma	Mammary gland		very low	very low			References: Cellurale C, PLoS One 2010;5(8):
Mesodermal cell/mesoblast sarcoma	Mesodermal cell/mesoblast		very low	low			References: Cellurale C, PLoS One 2010;5(8):
(Unspecified organ) carcinoma	(Unspecified organ)		very low	very low			References: Cellurale C, PLoS One 2010;5(8):
(Unspecified organ) tumor	(Unspecified organ)				100		References: Cellurale C, PLoS One 2010;5(8):

Models