Strain SummaryBALB/cJ-Mapk9tm1Flv Trp53tm1Tyj
Strain Name |
BALB/cJ-Mapk9tm1Flv Trp53tm1Tyj |
Strain Type(s) |
targeted mutation (knockout) |
Strain Synonym(s) |
Jnk2-/- Trp53-/- • Jnk2-/- Trp53-/- BALB/c |
Description |
Double homozygous mice. This cohort was generated by crossing congenic BALB/cJ mice carrying each of the mutations. The genetic background also contained some 129S2/SvPas. |
Strain Genetics |
Mapk9tm1Flv / Mapk9tm1Flv |
Trp53tm1Tyj / Trp53tm1Tyj |
Frequency | ||||||||
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Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Blood vessel hemangiosarcoma | Blood vessel |
moderate |
moderate |
References: Cellurale C, PLoS One 2010;5(8): |
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Leukocyte lymphoma | Leukocyte |
high |
high |
References: Cellurale C, PLoS One 2010;5(8): |
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Mammary gland carcinoma | Mammary gland |
0 |
0 |
References: Cellurale C, PLoS One 2010;5(8): |
||||
Mesodermal cell/mesoblast sarcoma | Mesodermal cell/mesoblast |
moderate |
moderate |
References: Cellurale C, PLoS One 2010;5(8): |
||||
(Unspecified organ) carcinoma | (Unspecified organ) |
0 |
0 |
References: Cellurale C, PLoS One 2010;5(8): |
||||
(Unspecified organ) tumor | (Unspecified organ) |
100 |
References: Cellurale C, PLoS One 2010;5(8): |